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NCT04647539 Clinical Trial

Emerging Invasive Fungal Infections in Critically Ill Patients

Fungal Infection Clinical Trial

— EIFI  

Official title:
Emerging Invasive Fungal Infections in Critically Ill Patients: Epidemiological Trends, Clinical Features and Outcomes

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04647539
Other study ID # RECHMPL20_0626
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2006
Est. completion date November 23, 2020

Study information
Verified date November 2020
Source University Hospital, Montpellier
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Rationale: Beside Candida and Aspergillus, emerging invasive fungal infections (EIFIs) are increasing in intensive care setting and are associated with high morbidity and mortality. However, data are scarce, particularly in ICU settings and for EIFIs other than mucormycosis. Objectives: to describe epidemiological trends and clinical features of EIFIs in intensive care units (ICU) and to assess their outcome. Methods: All records of adult patients diagnosed with an EIFI in a medical ICU between 2006 and 2019 were analyzed retrospectively. In-ICU mortality was assessed, then factors associated with mortality were identified. Survival at day-90 was calculated by the Kaplan-Meier method.

Recruitment information / eligibility
Status Completed
Enrollment 26
Est. completion date November 23, 2020
Est. primary completion date December 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years to 99 Years
Eligibility Inclusion criteria: - Adults (= 18 years old) with at least 1 positive culture for molds other than candida and aspergillosis Exclusion criteria: - Age < 18, pregnancy

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Uhmontpellier Montpellier

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary mortality mortality at ICU admission
Secondary Mucormycosis Mucormycosis at ICU admission
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