Burden, Mortality and Supply Costs in Intensive Care Unit Patients — PLV_Ulm  

Frailty Clinical Trial

Official title: Burden, Mortality and Supply Costs in Intensive Care Unit Patients. Health Services Research.

Status Recruiting

Clinical Trial Summary

This study systematically observes in a pragmatic trail under real world conditions the association between strategies of therapy (maximal therapy, withhold, withdraw) and treatment success in three endpoint related initial risk groups (high, intermediate, low risk) regarding three endpoints (burden, mortality and supply costs).

Clinical Trial Description

This study systematically observes in a pragmatic trail under real world conditions the association between strategies of therapy (maximal therapy, withhold, withdraw) and treatment success in three endpoint related initial risk groups (high, intermediate, low risk) regarding three endpoints (burden, mortality and supply costs).

The 3 endpoints and 3 respective risk groups (high, intermediate, low) are

1. Endpoint burden of care due to Clinical Frailty Scale (Frailty) high 7 - 9 intermediate 5 - 6 low 1 - 4

2. Endpoint mortality due to severity of disease regarding Simplified Acute Physiology Score (SAPS) II score values high SAPS II > 70, suspected mortality > 40% intermediate SAPS II > 40 - 70, suspected mortality 10 - 40% low SAPS II ≤ 40, suspected mortality < 10%

3. Endpoint supply costs due to number of organ systems to be supported or replaced high ≥ 3 organ systems replaced intermediate 1 - 2 organ systems replaced low 0 - 2 organ systems replaced ;

Related Conditions & MeSH terms

• Burden, Dependency
• Critical Illness
• Critically Ill Patient
• Death
• End-of-life Care
• Frailty
• Intensive Care Unit
• Mortality
• Multiple Organ Failure

• NCT number: NCT04094428
• Study type: Observational
• Source: University of Ulm
• Contact: Manfred Weiss, MD, MBA
• Phone: +49 - (0)731-500
• Email: manfred.weiss@uniklinik-ulm.de
• Status: Recruiting
• Start date: October 21, 2019
• Completion date: September 30, 2026