Fracture Non Union Clinical Trial
Official title:
Results of the Staged Surgical Approach for Management of Infected Un-united Femoral Shaft Fractures in Adults
Assessment of the efficacy of the multistage technique in the eradication of infection and achieving the union of traumatic infected femoral un-united shaft fractures in adult patients for one year follow up.
All cases will be treated by the induced membrane technique in two stages. In the first stage, thorough debridement of the infected bone and soft tissues and copious lavage will be done. After radical debridement, primary fixation will be done by either external fixation or antibiotic cement coated internally fixed implants.If there is a bone defect, it will be measured and filled with an antibiotic-impregnated (PMMA) cement spacer. The second stage procedure will be performed 4 to 8 weeks after the first one if soft tissue permits and only if there is no clinical or biochemical evidence of ongoing infection as indicated by normal white blood cell count, C-reactive protein, and erythrocyte sedimentation rate. It includes the exchange of the antibiotic cement spacer by a cancellous bone graft. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT03875963 -
Antibiotic Loaded Calcium Sulfate RCT
|
N/A |