Neurofunctional Correlates of Intentional Actions Towards Food Stimuli

Food Preferences Clinical Trial

Official title:

Neurofunctional Correlates of Intentional Actions Towards Food Stimuli

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04662606
• Other study ID #: CONSUME
• Status: Recruiting
• Phase: N/A
• Start date: September 12, 2020
• Est. completion date: December 1, 2022

Study information

• Verified date: December 2020
• Source: Istituto Ortopedico Galeazzi
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this project, the investigators will explore the cognitive neuroscience of intentional action in relation to food behaviour. To unravel how the brain systems involved in intentional control of actions and how these interact with the reward system in different physiological conditions and in relation to lean-weight or obesity, the investigators will manipulate the degree of intentionality of the behaviours under examination and the level of satiety of the participants.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 48
• Est. completion date: December 1, 2022
• Est. primary completion date: September 12, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Normal weight (normal BMI)
• No MRI controindications
• No neurological or cognitive problems

Exclusion Criteria:

• Underweight or overweight
• MRI controindications
• Neurological or cognitive problems

Related Conditions & MeSH terms

• Food Preferences

Intervention

Behavioral:
• Consumption of a standard meal prior to the fMRI data collection
Consumption of a standard meal prior to the fMRI data collection

Locations

Country	Name	City	State
Italy	IRCCS Istituto Ortopedico Galeazzi	Milan	Milano
Italy	IRCCS Galeazzi	Milano	Italia

Sponsors (1)

Lead Sponsor	Collaborator
Istituto Ortopedico Galeazzi

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	BOLD (Blood Oxygen Level Dependent) signal	The investigators will measure the changes of the hemodynamic response (BOLD signal) recorded in the whole brain during the execution of the different experimental tasks (e.g. intentionally guided actions towards stimuli of high or low calories food vs externally guided actions towards stimuli of high or low calories food), in the two groups (fasted and satiated subjects).	This outcome will be measured on the recruitment day