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Flu clinical trials

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NCT ID: NCT03694808 Completed - Flu Clinical Trials

FLUAD vs. FLUZONE HD Influenza Vaccine in Residents of Long Term Care

Start date: September 23, 2018
Phase: Phase 4
Study type: Interventional

Adjuvanted flu vaccine, Fluad, is not immunologically inferior to HD influenza vaccine in older persons living in long-term care.

NCT ID: NCT03430089 Completed - Influenza Clinical Trials

Safety of a Single Dose or Two Doses of Shenzhen Quadrivalent Influenza Vaccine

Start date: February 22, 2019
Phase: Phase 1
Study type: Interventional

This phase I-like, open-label, monocenter, descriptive, single-arm clinical safety study will investigate the Shenzhen quadrivalent influenza vaccine (Shz QIV) in 100 participants aged 6 months and older in China. Participants aged 9 years or more will receive a single dose of Shz QIV, and participants aged 6 months to 8 years will receive two doses of Shz QIV administered 28 days apart.

NCT ID: NCT03344029 Completed - Influenza Clinical Trials

Immunogenicity and Safety of the Shenzhen Trivalent Inactivated Influenza Vaccine Versus a Trivalent Influenza Vaccine Comparator in Chinese Subjects 18 to 59 Years

Start date: November 3, 2017
Phase: Phase 4
Study type: Interventional

This was a blind-observer, monocenter, randomized, comparative, Phase IV study designed to evaluate the immunogenicity and safety of the Sanofi Pasteur Shenzhen Trivalent Influenza Vaccine (SP Shz TIV) versus the Trivalent Influenza Vaccine manufactured by Hualan Biological Engineering Inc (Hualan TIV) comparator in healthy Chinese participants aged 18 to 59 years.

NCT ID: NCT03308825 Completed - Influenza Clinical Trials

Safety and Immunogenicity of Fluzone® Quadrivalent and Fluzone® High-Dose, Influenza Vaccines

Start date: September 11, 2017
Phase: Phase 4
Study type: Interventional

The aim of the study was to describe the safety and immunogenicity of the 2017-2018 formulation of Fluzone Quadrivalent vaccine in children 6 months to < 9 years of age, and in adults 18 to < 65 years of age, and to describe the safety and immunogenicity of the 2017-2018 formulation of Fluzone High-Dose vaccine in adults ≥ 65 years of age.

NCT ID: NCT03293979 Completed - Flu Clinical Trials

Alere i FluA*B Biologic Test Relocated in Emergency Service for Flu Diagnosis

Start date: January 22, 2016
Phase:
Study type: Observational

It appears that the heavyness of flu pathology, the diagnosis limits and the validity of it was well studied in the last years.However, the economical impact and the organisation benefit in emergency service is not yet evaluated Our purpose is to study the impact of implementation of fast flu diagnosis by molecular biology available in emergency service in the economic field .

NCT ID: NCT03212716 Terminated - Flu Clinical Trials

Efficiency of Antagonist Drugs of the Cellular Transcriptomic Signature of Influenza A Virus Infection.

FLUNEXT
Start date: December 23, 2017
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the possibility to repropose marketed drugs as antiviral ones, based on their ability to reverse the transcriptomic signature of the infected cells. This strategy has to be considered is the context of emerging viral diseases and of increase of resistance to antivirals. Concerning infection by Influenza viruses, the main drugs were identified and evaluated on in vitro and in vivo models: diltiazem. Therefore, it will be assess the efficacy of these the drug, compared to placebo, to treat severe flu.

NCT ID: NCT03189537 Completed - Influenza, Human Clinical Trials

Study of Post-Exposure Ingavirin® Prophylaxis of Influenza and Acute Respiratory Viral Infections

Start date: October 3, 2010
Phase: Phase 3
Study type: Interventional

The purpose of the study was to evaluate efficacy of prophylactic Ingavirin intake by people having contact with sick people infected with influenza and other acute respiratory viral infections

NCT ID: NCT03035396 Completed - Influenza Clinical Trials

Clinical Performance of the Diassess Influenza A and B Test

Start date: December 29, 2016
Phase: N/A
Study type: Interventional

The primary objective of this study is device feasibility of the Diassess Influenza A and B Test

NCT ID: NCT02822105 Completed - Flu Clinical Trials

Safety and Immunogenicity Study of H3N2 M2SR Monovalent Influenza Vaccine in Healthy Volunteers

Start date: June 2016
Phase: Phase 1
Study type: Interventional

The purpose is of this study is to assess the safety and tolerability of three dose levels of H3N2 M2SR influenza vaccine versus placebo delivered intranasally to healthy adult subjects.

NCT ID: NCT02188810 Active, not recruiting - Flu Clinical Trials

Safety and Reactogenicity of a PAL Combined With Seasonal Flu Vaccine in Healthy Adults

Start date: April 2014
Phase: Phase 1
Study type: Interventional

This is a phase 1, research study is looking at the safety and acceptability of a new vaccine adjuvant (immune booster) called PAL when combined with the seasonal flu vaccine (Fluviral) to test the safety and effectiveness of new vaccines and medications on healthy volunteers. The study will enroll approximately 48 healthy adult participants, and occur over 3 years. In the first six months/180 days of the study participants will have visits to the study site during which safety and immunogenicity outcomes will be measured. From Day 181 to Year 3, participants will be contacted by telephone or email to collect information on any adverse events.