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Clinical Trial Summary

Microdialysis is admitted to be reliable by numerous surgeons to monitor flaps. Nevertheless, a few authors reported follow up with microdialysis in bone free flaps, and they all describe the position of the catheter in the surrounding soft tissue muscle which is not the accurate reflect of bone vascularisation. The aim of this study is to determine the lactate/pyruvate ratio mean value in bone free flaps with a microdialysis catheter directly positioned in the bone tissue.


Clinical Trial Description

Failure rate of facial reconstructive surgery with bone free flaps varies between 11 and 25%. In case of buried bone free flaps, the follow up is even more difficult. Monitoring methods, such as the implantable Doppler system, laser Doppler flowmetry and microdialysis have been developped in the last 15 years. Ferguson et al. show a false positive rate of 31% with implantable doppler monitoring of buried flaps. The purpose of this study is to to determine the lactate/pyruvate ratio mean value in bone free flaps with a microdialysis catheter directly positioned in the bone tissue. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03935139
Study type Interventional
Source Centre Hospitalier Universitaire, Amiens
Contact Stéphanie Dakpe, MD
Phone (33)322089050
Email dakpe.stephanie@chu-amiens.fr
Status Recruiting
Phase N/A
Start date July 22, 2019
Completion date July 2023

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