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NCT05567614 Clinical Trial

Platelets Indices and Its Role to Predict Liver Fibrosis in Patients With Chronic Hepatitis B Infection

Fibrosis, Liver Clinical Trial

Official title:
Platelets Indices and Its Role to Predict Liver Fibrosis in Patients With Chronic Hepatitis B Infection

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05567614
Other study ID # Platelets and liver fibrosis
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date October 20, 2022
Est. completion date December 15, 2023

Study information
Verified date October 2022
Source Assiut University
Contact Wafaa Ad Abdelghany, resident DR
Phone 01118845248
Email wafaaadel789@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Platelets indices and its role to predict liver Fibrosis in patients with chronic hepatitis B infection

Description:

Patients with chronic Hepatitis B infection will be collected and will do liver fibroscan to predict the degree of liver Fibrosis and correlate between the role of platelets count and degree of liver Fibrosis in patients with Chronic hepatitis B virus

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 75
Est. completion date December 15, 2023
Est. primary completion date August 15, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: - Age from 18 to 70 years - without a history of clinical illness Exclusion Criteria: - with other hepatitis virus infection; (b) with alcoholic liver disease; (c) with any disease related to fibrosis (such as connective tissue diseases, chronic obstructive pulmonary disease, kidney failure, tumors, and so on); (d) have received any anti-fibrosis therapy; and (e) pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Radiation:
• Liver Fibroscan
Patients with CHB virus will do liver fibroscan and correlat between platelets count and degree of liver fibrosis

Locations
Country Name City State
Egypt AssiutU Assiut

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (2)

Tan YW, Zhou XB, Ye Y, He C, Ge GH. Diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index and liver stiffness measurement in hepatitis B virus-infected patients with persistently normal alanine aminotransferase. World J Gastroenterol. 2017 Aug 21;23(31):5746-5754. doi: 10.3748/wjg.v23.i31.5746. — View Citation

Zhong LK, Zhang G, Luo SY, Yin W, Song HY. The value of platelet count in evaluating the degree of liver fibrosis in patients with chronic hepatitis B. J Clin Lab Anal. 2020 Jul;34(7):e23270. doi: 10.1002/jcla.23270. Epub 2020 May 4. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Platelets indices and its role to predict liver Fibrosis in patients with chronic hepatitis B infection Correlation between platelets count and degree of liver Fibrosis in patients with chronic hepatitis B virus through liver fibroscan Two years
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