Observational Study About In-patients Admitted With Fever

Fever Clinical Trial

Official title:

Characteristic, Diagnosis and Prognosis of Patients Admitted With Fever in Department of Infectious Diseases

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05422651
• Other study ID #: Xiangya fever project
• Status: Recruiting
• Start date: June 1, 2022
• Est. completion date: August 1, 2026

Study information

• Verified date: June 2022
• Source: Xiangya Hospital of Central South University
• Contact: Yan Huang
• Phone: 13874854142
• Email: drhyan[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Fever is a common symptom in patients with infectious diseases. This study hopes to understand the epidemiological characteristics of patients hospitalized due to fever through observational research, including: clinical characteristics, etiology of fever and prognosis after treatment. So as to further search for biochemical or other serological indicators to predict the diagnosis and prognosis of infectious fever and non-infectious fever, and try to establish relevant prediction models.

Description:

This study mainly prospectively analyze the clinical data of patients with fever with/without other symptoms admitted to the department of infectious diseases, Xiangya Hospital of Central South University, to analyze the epidemiological characteristics, diagnosis and prognosis of these patients. This is an observational study. All subjects will receive the currently recognized routine test of fever according to their disease and corresponding etiological treatment if needed. The researchers will collect various clinical examination indexes of the subjects in the process of diagnosis and treatment, including but not limited to white blood cells, C-reactive protein, Procalcitonin, ferritin, blood culture, therapeutic drugs, etc. Etiology and prognosis of patients will be recorded. Blood samples, urine and stool samples of all subjects will be taken after enrollment and stored for probably testing in the future. This study has no additional intervention and treatment for subjects. All subjects will sign informed consent.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 500
• Est. completion date: August 1, 2026
• Est. primary completion date: August 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 14 Years to 90 Years

Eligibility

Inclusion Criteria:

• all patients admitted to department of infectious diseases because of fever

Exclusion Criteria:

• patents who refuse to sign informed consent

Related Conditions & MeSH terms

• Fever

Locations

Country	Name	City	State
China	Department of Infectious Disease, Xiangya Hospital, Central South University	Changsha	Hunan

Sponsors (1)

Lead Sponsor	Collaborator
Xiangya Hospital of Central South University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Length of fever	The interval between the onset of fever and the return of body temperature to normal after medical intervention or spontaneous remission	1 month after admission
Secondary	Fever associated mortality	mortality of patients due to conditions associated with fever	3 months