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Observational Study to Assess Protection to Mumps in Children Received One-dose Mumps-containing Vaccine

Fever Clinical Trial

Official title:
Observational Cohort Study to Evaluate Immunogenicity, Protection, and Persistence of Antibody to Mumps in 3-7 Years' Children Received One-dose Mumps-containing Vaccine

Clinical Trial Summary

This study was aimed to conduct a 3-year perspective study to observe the immunological effect of one-dose mumps-containing vaccine, monitor the incidence of mumps in vaccinated population aged 3-7 years，and provide basis for adjusting MMR immunization strategy in Jiangsu province, China.

Clinical Trial Description

in 3-7 years old children with high risk of mumps, epidemiological investigation of the serum IgG antibody level were conducted, and then a prospective observational cohort was established in the population with a history of mumps vaccination, and the incidence of mumps in each antibody level group will be observed, the relationship between different antibody levels and the incidence after mumps vaccinated were analyzed, to explore attenuation of mumps IgG antibody levels in the body,S79 vaccine strain against F genotype mumps' antigenic cross-reactivity and the protective effect of antibodies. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02901990
Study type Observational
Source Jiangsu Province Centers for Disease Control and Prevention
Contact
Status Completed
Phase N/A
Start date October 1, 2015
Completion date February 2, 2017
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