Fetal Growth Retardation Clinical Trial
Official title:
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)
This study aims to establish a multicenter cohort of FGR high-risk pregnant women, and aims to construct a combined predictive model for FGR by combining basic characteristics, medical history, early pregnancy ultrasound, and biomarkers.
Most FGR predictions are based on early pregnancy screening models for preeclampsia or mid-pregnancy screening models for Down syndrome, which have limited value. And specially clinical screening for maternal vascular malperfusion fetal growth restriction (MVM-FGR) in the general population was not recommended by most guidelines. This study aims to establish a multicenter, prospective cohort of FGR high-risk pregnant women. Baseline characteristics, and prenatal ultrasound evaluations of fetal growth, placental and maternal-fetal Doppler blood flow, and structural assessments, will be collected. Maternal serum and plasma will also be collected for biomarker testing. Fetal growth, information on pregnancy status, delivery information, and placental pathology test results will be collected. By combining medical history, ultrasound, serum, and plasma biomarkers, we will establish an combined predictive model for prediction of MVM-FGR at early pregnancy. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05899101 -
The Impact of Opioid and Cannabis Exposure on Fetal Growth
|
||
| Completed |
NCT04502823 -
Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler
|
N/A | |
| Not yet recruiting |
NCT03625518 -
Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes
|
Early Phase 1 | |
| Completed |
NCT05176041 -
SLE Therapy Changes in Pregnancy and Relation to Pregnancy Outcome
|
||
| Completed |
NCT02379728 -
Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth
|
N/A | |
| Completed |
NCT01695070 -
Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies
|
Phase 4 | |
| Completed |
NCT01352234 -
Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia
|
Phase 4 | |
| Not yet recruiting |
NCT05284474 -
Management of Early-onset Fetal Growth Restriction: Angiogenic Factors Versus Feto-placental Doppler
|
N/A | |
| Completed |
NCT04289350 -
Day to Day Variation in Fetal Heart Rate Variability
|
||
| Recruiting |
NCT03662178 -
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
|
||
| Recruiting |
NCT05023161 -
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
|
||
| Completed |
NCT02590536 -
A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction
|
Phase 3 | |
| Not yet recruiting |
NCT05029778 -
Arginine + Citrulline as a Supplement for Weight Gain in Fetus With a Decrease in Their Growth Curve
|
Phase 4 | |
| Recruiting |
NCT05576207 -
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
|
N/A | |
| Active, not recruiting |
NCT05160649 -
Effect of Covid 19 Infection on Fetomaternal Outcome
|
||
| Completed |
NCT02280031 -
Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial.
|
Phase 2 | |
| Recruiting |
NCT04389099 -
MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo
|
||
| Recruiting |
NCT06039319 -
Acute Effects of Maternal Exercise and the Growth Restricted Pregnancy
|
||
| Recruiting |
NCT05651347 -
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
|
Phase 3 | |
| Recruiting |
NCT02336243 -
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
|
Phase 3 |