Fetal Brain Injury Clinical Trial
Official title:
Detecting and Quantifying Sulci and White Matter in Fetus' Brain Along the Third Stage of Gestation
| Verified date | June 2017 |
| Source | Rambam Health Care Campus |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational [Patient Registry] |
Gyrogenesis is an ontogenic process that transforms the smooth (lissencephalic) cortex
toward its mature, convolved (gyrencephalic) state. A tortuous, branching and deepening
pattern of sulci and fissures outlines for a well-developed cortex.
The aim of this study is to find an algorithm that can detect the sulci in ultrasound images
of fetus' brain and measure the length of it. This algorithm can be used for research
demands like learning the development of the brain from embryo stages until the birth of the
baby
| Status | Active, not recruiting |
| Enrollment | 150 |
| Est. completion date | January 2018 |
| Est. primary completion date | September 2017 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Female |
| Age group | 18 Years to 35 Years |
| Eligibility |
Inclusion Criteria: - Pregnant women between the ages of 18-35 - Gestational age between 25-40 weeks - Low risk pregnancies Exclusion Criteria: - Multiple gestation - Fetal brain abnormality |
| Country | Name | City | State |
|---|---|---|---|
| Israel | Rambam Health Care Campus | Haifa |
| Lead Sponsor | Collaborator |
|---|---|
| Rambam Health Care Campus |
Israel,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | morphological changes of the developing fetal brain | Ultrasound measurements of the fetal brain sulcation by a computerized algorithm | 9 months |