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Femur Head Necrosis clinical trials

View clinical trials related to Femur Head Necrosis.

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NCT ID: NCT06410079 Not yet recruiting - Femur Head Necrosis Clinical Trials

Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing

PTH-50
Start date: June 1, 2024
Phase:
Study type: Observational [Patient Registry]

This study aims to evaluate the return to activity in younger patients under 50 years old after undergoing either total hip replacement (THR) or hip resurfacing, as performed in everyday practice. This research will be observational, meaning patients will not be randomly assigned to different treatment groups. To objectively assess participents; return to everyday, professional, and sports activities, validated questionnaires will be sent to participents in addition to routine clinical practice. The study will be prospective and comparative based on the type of prostheses used. In order to capture the current practices of surgeons performing THR in participents under 50 years old in France, the study will be conducted at multiple centers across the country. Since hip resurfacing is performed only in certain centers, approximately half of the participating centers are experienced in this technique. Participents typically resume activity between 3 and 6 months after THR. One year of post-operative follow-up allows for an accurate assessment of participents; recovery, unaffected by the surgery. Participents ; physical activity levels will be evaluated using the UCLA Activity Scale developed by surgeons to assess the activity levels of patients undergoing hip and arthroplasty.

NCT ID: NCT05982054 Recruiting - Clinical trials for Avascular Necrosis of the Femoral Head

Bone Marrow Cells With Core Decompression for AVN Treatment

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

Avascular necrosis of the femoral head (AVN) is a progressive pathological process resulting from disruption of blood supply to the femoral head and elevation of intraosseous pressure. total hip arthroplasty is frequently the only durable option for pain relief and restoration of function. this is a single armed study to be done from July 2023 till January 2024, the total number of patients anticipated is 10, total joints treated around 20, The procedure includes core decompression with autologous bone marrow derived mononuclear cell injection inside the femoral head using local anesthesia ultrasound and fluoroscopy guided without drilling.

NCT ID: NCT04943328 Active, not recruiting - Clinical trials for Rheumatoid Arthritis

Cemented TrendHip® - Multicenter PMCF Study on Total Indications

TRESTI
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

This Post Market Clinical Follow-Up (PMCF) study to evaluate the performance and safety of the cemented TrendHip® stem in a prospective follow-up study with patients who underwent a hip arthroplasty with the investigational product (representative of usual clinical practice), at two follow-up examinations

NCT ID: NCT03753282 Withdrawn - Clinical trials for Avascular Necrosis of the Femoral Head

Outcome After Avascular Necrosis of the Femoral Head in Young Patients

AVN
Start date: January 30, 2019
Phase:
Study type: Observational

1. The course of AVN between Initial diagnosis and total hip replacement (THA) is analysed. The impact of early interventions versus conservative therapy in AVN before THA will be evaluated. 2. The short and long term outcomes of AVN patients undergoing THA with respect to complications, reoperations and quality of life are investigated. Potential risk factors for adverse outcomes will be investigated.

NCT ID: NCT03685110 Active, not recruiting - Clinical trials for Degenerative Osteoarthritis

CoreHip - Post Market Clinical Follow-Up Study

Start date: October 16, 2018
Phase:
Study type: Observational

The study is designed as a prospective, non-interventional multicentre cohort study. The product under Investigation will be used in Routine clinical practice and according to the authorized Instructions for Use (IfU). Aim of this observational study is to collect clinical and radiological results of the CoreHip® endoprosthesis system in a Standard Patient Population and when used in Routine clinical practice.

NCT ID: NCT03639532 Completed - Osteoarthritis, Hip Clinical Trials

Ceramic-on-Ceramic Versus Ceramic-on-HXLPE THA

Start date: January 1, 2000
Phase: Phase 4
Study type: Interventional

Methods to reduce the revision rate of total hip arthroplasties (THAs) because of wear-related issues are important to examine, particularly because younger patients have a disproportionately high risk of revision. The investigators hoped to follow up patients and see if long-term Harris hip scores and WOMAC scores better in younger patients with a ceramic-on-ceramic (COC) THA compared with those with a ceramic-on-highly-cross-linked polyethylene (COP) THA.

NCT ID: NCT03405974 Recruiting - Clinical trials for Osteonecrosis of Femoral Head

Aspirin in the Prevention of Collapse in Osteonecrosis of the Hip

Start date: October 12, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if prolonged administration of low-dose aspirin will prevent the progression of early-stage osteonecrosis of the femoral head and may even reduce the extent of involvement of the femoral head by the necrotic process The design is intended to be parallel group where a total of 114 patients will be randomized in a 1:1 ratio to the treatment (ASA) and the control (Placebo) arms.

NCT ID: NCT03180463 Suspended - Clinical trials for Osteonecrosis of Femoral Head

The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH)

Start date: December 31, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purposes of the study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating osteonecrosis of femoral head patients.

NCT ID: NCT02972762 Enrolling by invitation - Femur Head Necrosis Clinical Trials

Anesthesia Depth's Influence on Postoperative Delirium

Start date: November 2016
Phase: Early Phase 1
Study type: Interventional

The investigators,according to the eligibility criteria,plane to choose 80 elderly anticipates who will undergo selective hip replacement surgery.This participants will be randomly divided into 2 groups:light anesthesia depth group(L Group) and deep anesthesia depth group (D Group).Before anesthesia induction,each participant will be given lumbar plexus and sciatic nerve block in order to control pain of interoperative and postoperative.During operation period,the L Group will be kept in light anesthesia depth(BIS:50-60),while the D group will be kept in deep anesthesia depth(BIS:35-45)--The BIS values in the range of 30-60 have been recommended in general anesthesia.After operation,a PCIA(patient controlled intravenous analgesia) analgesia pump will be given to each participant to control postoperative pain. The investigator will evaluate the mental state of participant with MMSE(mini-mental state examination) before surgery and review each participant with a CAM-CR for 3 days after surgery to assess the situation of postoperation delirium.intraoperative awareness,postoperative pain will also be investigated in postoperative days 1, 2, 3.

NCT ID: NCT02877472 Recruiting - Clinical trials for Femoral Neck Fracture

Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head

Start date: May 2015
Phase: N/A
Study type: Interventional

To confirm 1) whether, compared with core decompression alone, core decompression with porous tantalum rod implantation improves the hip joint function of patients with avascular necrosis of the femoral head after femoral neck fracture surgery, 2) whether porous tantalum rod shows favorable biocompatibility with the human body, and 3) whether this treatment method is feasible for treating avascular necrosis of the femoral head after femoral neck fracture surgery.