Clinical Trials Logo
  1. Home
  2. Femoral Neck Fractures
  3. NCT00749710

Blood Loss and Complications of Internal Fixation of Femoral Neck Fractures in Patients Treated With Clopidogrel

Femoral Neck Fractures Clinical Trial

Official title:
Blood Loss and Complications of Internal Fixation of Femoral Neck Fractures in Patients Treated With Clopidogrel

Clinical Trial Summary

Patients suffering from femoral neck or pertrochanteric fractures have a high rate of mortality and morbidity associated mainly with deconditioning and immobilization. Surgical management including open reduction and internaql fixation has been shown to reduce complication and improve outcome in such patients. Delay of surgery produces less optimal results and is associated with higher morbidity even after 24-48 hours of fracture event.

Patients treated with platelet antiaggregants are exposed to higher blood loss during surgery and related complications, as demonstrated in patients treated with Aspirin. However, cessation of antiaggregant therapy before surgery may be associated with complications of a hypercoagulable state and surgery delay.

Clpopidogrel is a fairly new approved antiaggregant drug indicated in cases of failed aspirin treatment in ischemic heart disease and cerebrovascular disease patients as well as in primary prevention of stent restenosis.

No data regarding complications of hip surgery in patients treated with Clpopidogrel is available.

Study hypothesis:

Definitive surgical treatment of patients treated with clopidogrel undergoing open reduction and internal fixation of pertrochnteric and femoral neck fractures is safe although associated with more extensive blood loss during surgery and postoperative wound complications.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00749710
Study type Interventional
Source Tel-Aviv Sourasky Medical Center
Contact Ely Steinberg, MD
Phone 972-52-4266346
Email steinberge@tasmc.health.gov.il
Status Not yet recruiting
Phase N/A
Start date September 2008
Completion date December 2012
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05505604 - PENG vs FICB for Hip Fracture in ED Patients N/A
Recruiting NCT04462172 - A Prospective Multicenter Cohort Study About Internal Fixation Using FNS Versus MCS for Femoral Neck Fracture N/A
Enrolling by invitation NCT04110639 - Intraoperative Monitoring of Femoral Head Perfusion N/A
Terminated NCT01908751 - Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2) Phase 3
Recruiting NCT01934049 - Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty Phase 4
Recruiting NCT01219088 - Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw Phase 4
Active, not recruiting NCT00491673 - A Prospective Randomized Trial of Uncemented Versus Cemented Hemiarthroplasty for Displaced Femoral Neck Fractures N/A
Completed NCT00464230 - Hemiarthroplasty or Internal Fixation for Displaced Femoral Neck Fractures Phase 4
Recruiting NCT03966716 - Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR) N/A
Recruiting NCT05227924 - Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty
Completed NCT03666637 - Femoral Neck Fracture in Adult and Avascular Necrosis and Nonunion
Terminated NCT03721835 - Safety Study of Femoral Neck Fracture System N/A
Not yet recruiting NCT04408053 - Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture Phase 3
Recruiting NCT04577261 - FNS (FEMORAL NECK SYSTEM) Study
Recruiting NCT04589598 - Femoral Neck System and Multiple Cannulated Screws in Femoral Neck Fracture N/A
Not yet recruiting NCT06078371 - Opioid-Free Pain Treatment in Trauma Patients N/A
Withdrawn NCT02198820 - Practice Survey on Femoral Neck Fractures and the Incidence of Type of Anesthesia on Patient Outcome N/A
Active, not recruiting NCT02246335 - Hemiarthroplasty Compared to Total Hip Arthroplasty for Displaced Femoral Neck Fractures in the Elderly-elderly N/A
Not yet recruiting NCT00926666 - A Dose Finding Study for Pain Relief of a Broken Hip Phase 4
Withdrawn NCT00317837 - Bipolar Versus Unipolar Hemiarthroplasty for Patients With a Hip Fracture N/A