Plate Fixation of Distal Femur Fractures: A Protocol for a Study of Two

Status Completed

Clinical Trial Summary

Internal fixation of femur fractures improves alignment and provides stability to the bone and the surrounding soft tissues. This generally allows for early motion of the adjacent joints; thus maximizing overall function of the limb. Open reduction and internal fixation with plates and screws is the standard method that has been used in the treatment of distal femoral fractures. One common traditional method of internal fixation is the 95-degree angled blade plate. Recent advances in technology for distal femur fractures include the LCP™ Condylar Plate. This implant differs from the blade plate, because the LCP offers multiple points of fixed angle contact between the plate and screws in the distal femur. The introduction of plates with the option of locked screws has provided means to increase the rigidity of fixation in osteoporotic bone or in periarticular fractures with a small distal segment, and the LCP may be technically easier to apply than the blade plate. To the investigators' knowledge, there have been no published clinical or biomechanical studies specific to the LCP Condylar Plate, although the early results of LCP implants for other fractures are promising. The investigators believe that locked plating represents a valuable advancement in fracture treatment. However, the limitations of this new technology and the indications for its use have not been completely elucidated. Furthermore, the cost of the new technology is approximately seven times more than the traditional treatment. This is a randomized, prospective, multi-center study to compare the blade plate and the LCP in the distal femur. All patients 16 years of age or older, regardless of race or gender, with a supracondylar fracture of distal femur will be considered. Whether patients are treated with a blade plate or/and LCP, they will be receiving standard orthopedic care for their injury. Neither of these methods currently places a patient at increased surgical or post-surgical risk for problems with infection, nonunion, malunion, or other complications. Because of the study, early and late complication rates and functional outcomes after these treatments may be better defined, allowing for optimization of care of people with these injuries in the future. This should reduce not only direct and indirect costs to the individual, but also costs to society.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00644397
Study type	Observational
Source	MetroHealth Medical Center
Contact
Status	Completed
Phase
Start date	May 2006
Completion date	January 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02272972` - Performance Improvement Program on Imaging II
Terminated	`NCT02679560` - Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures	Phase 2
Terminated	`NCT00822159` - Influence of Bone Strength Measured by DensiProbe on Bone Related Fixation Failure	N/A
Recruiting	`NCT05272631` - Depuy Synthes Lower Extremity Shaft Nail Registry
Recruiting	`NCT02672696` - Interest of Navigation for the Treatment of Pertrochanteric Fractures With the Gamma 3 Nail	N/A
Terminated	`NCT01553630` - Reamed Locked Plating - Metaphyseal Fractures of the Distal Femur and Tibia	N/A
Completed	`NCT00962910` - European Quality of Care Pathways Study on Proximal Femur Fracture (EQCP-PFF)	N/A
Completed	`NCT05737459` - Sedation and Postoperative Cognitive Functions
Active, not recruiting	`NCT01599221` - Observational Retrospective and Prospective Study on the Treatment of Femoral Fractures With EBA2	N/A
Completed	`NCT00552331` - Evaluation of the Effects of Less Invasive Stabilization System (LISS) Plating Techniques in Distal Femoral Fractures	Phase 4
Withdrawn	`NCT04865146` - A Study to Evaluate the Safety and Effectiveness of TRIGEN™ INTERTAN™ (10S Models)
Withdrawn	`NCT04626141` - Supracondylar Distal Femur Fractures and Abaloparatide	Phase 4
Recruiting	`NCT02658760` - Dexmedetomidine and Bupivacaine With Bupivacaine in Ultrasonography Guided Fascia Iliaca Compartment Block in Adults	Phase 3
Completed	`NCT03800186` - Influence of Age on Trauma Femoral Fractures
Completed	`NCT01548456` - Nails Versus Plates for Femur Fractures in Dar es Salaam, Tanzania	N/A
Completed	`NCT00509171` - Effect of a Novel Reamer-Irrigator-Aspirator on the Incidence of Fat Embolism	N/A
Completed	`NCT03822000` - Risk Factors and Complications Contributing to Mortality in Elderly Patients With Fall-Induced Femoral Fracture
Completed	`NCT06382584` - Impact of Treatment With Oral Anticoagulants of Patients With Fractures of the Upper End of the Femur
Completed	`NCT05172869` - Comparison of Two Different Approaches in the Fascia Iliaca Compartment Block in Femoral Fracture Surgery	N/A
Terminated	`NCT01294098` - Efficacy Study of Femoral Nerve Block in Children With a Femur Fracture	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Plate Fixation of Distal Femur Fractures: A Protocol for a Study of Two Plate Options

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms