Clinical Trials Logo
  1. Home
  2. Femoral Fracture
  3. NCT02069327
  4. Details
NCT02069327 Clinical Trial

The Role of Fat Emboli in the Trauma Inflammatory Response

Femoral Fracture Clinical Trial

Official title:
The Role of Fat Emboli in the Trauma Inflammatory Response

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02069327
Other study ID # Fat Emboli
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 2012
Est. completion date November 2014

Study information
Verified date March 2019
Source Poudre Valley Health System
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This is an observational study designed to investigate the role of fat emboli in patients who are undergoing a tibial or femoral fracture procedure in the operating room. The purpose of this study is to obtain samples of bone marrow and blood during tibial or femoral fracture procedures to understand the inflammatory response.

Description:

Bone marrow is routinely removed during a tibial or femoral fracture procedure; researchers will take samples for this study from bone marrow that has already been removed as part of this procedure. No additional marrow samples will be taken as part of this research study. Also, researchers will collect blood (about 4 teaspoons) for testing inflammatory response and coagulation. Researchers may need to insert an additional line to collect your blood.

Recruitment information / eligibility
Status Completed
Enrollment 9
Est. completion date November 2014
Est. primary completion date July 2014
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients undergoing a tibial or femoral fracture procedure in the operating room.

Exclusion Criteria:

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Medical Center of the Rockies Loveland Colorado

Sponsors (2)
Lead Sponsor Collaborator
Poudre Valley Health System Colorado State University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Inflammatory Response Samples will be tested using proteomic and metabolomic assays from samples of bone marrow reamed during intramedullary (IM) femoral nailing.
Blood samples drawn at the time of IM nailing will be tested to determine if clinically relevant amounts of marrow containing these inflammatory mediators are released into the bloodstream.		 One day
See also
  Status Clinical Trial Phase
Completed NCT05515718 - Effect of the Early Ultrasound-guided Femoral Nerve Block Performed by Emergency Physicians on Pre-operative Opioids Usage in Patients With Proximal Femoral Fractures N/A
Recruiting NCT04494672 - A Study to Verify if the Surgery for the Proximal Femur Fracture Can be Improved With the Help of a Navigation System N/A
Unknown status NCT01680120 - Dose Finding Study for Continuous Spinal Anaesthesia Phase 4
Recruiting NCT04015128 - A Post-Market Clinical Evaluation of the Treatment of Femur Fractures With the Femoral Nail GT
Active, not recruiting NCT04015154 - A Post-Market Clinical Evaluation of the Treatment of Femur Fractures With the Femoral Nail PF
Recruiting NCT05410587 - Fracture Monitor - Femur N/A
Completed NCT02983344 - Analgesia For Positioning Patient With Femur Fracture For Spinal Anaesthesia N/A
Terminated NCT00764959 - Retrospective Study of the Linear™ Hip Phase 4
Completed NCT03856502 - Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures N/A
Recruiting NCT05559736 - Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures N/A
Completed NCT03810092 - Analysis of the Relationship Between Early Postoperative Anemia and the Evolution of Autonomy at 6 Months in Patients 75 Years of Age and Older Operated on Following a Fracture of the Upper End of the Femur
Recruiting NCT05087667 - Study of the Effectiveness of a Polymer Cerclage System Compared to Cerclages Used in Standard Care (CERCPMCF) ) N/A
Recruiting NCT05523635 - Post Market Clinical Evaluation of Gamma 4
Recruiting NCT05274022 - Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture N/A
Terminated NCT01300520 - The Development of a Surgical Localizing Aid Medical Device N/A
Terminated NCT01141894 - Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture N/A
Recruiting NCT05668182 - A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects
Recruiting NCT05680987 - Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures N/A
Not yet recruiting NCT04918680 - Prospective Post-market Study Examining the Effectiveness of the EcoFit®
Terminated NCT03846102 - MORphine Use in the Fascia Iliaca Compartment Block With UltraSound Phase 4