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Feeding Disorder Neonatal clinical trials

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NCT ID: NCT04282655 Completed - Weight Gain Clinical Trials

Effect of Milk Warming on the Very Low Birth Weight Infant

VLBW
Start date: September 2, 2016
Phase: N/A
Study type: Interventional

This study will compare if using a continuous milk warmer to warm breast milk compared to the standard method of warming breast milk in a hot water bath improves weight gain and feeding tolerance in infants born at 32 weeks gestation or less over a ten-day period. The standard method does not keep the breast milk at a consistent temperature during the feeding. A continuous milk warmer maintains the breast milk at body temperature throughout the feeding. It is unknown which method improves weight gain and feeding tolerance in very low birth weight infants.

NCT ID: NCT04062851 Completed - Preterm Infant Clinical Trials

Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants

Start date: May 3, 2019
Phase: N/A
Study type: Interventional

The practice of checking gastric residuals is not evidence based. The amount of gastric residual volume (GRV) does not correlate with either feeding intolerance or development of NEC. We hypothesize that not monitoring GRV in infants with birth weights < 1,250 g, and who are being fed intermittently by gastric tube, will result in earlier attainment of full feeding. This is an unblinded randomized controlled trial where GRV will not be checked routinely in the intervention group.

NCT ID: NCT03743207 Completed - Prematurity Clinical Trials

Preterm Infants May Better Tolerate Warmer Feeds

Prematurity
Start date: October 1, 2012
Phase: N/A
Study type: Interventional

Feeding intolerance is frequent among preterm infants in neonatal intensive care units (NICUs). Although there are many studies about enteral nutrition strategies and content in preterm infants, no evidence-based standards exist for the optimal milk temperature for preterm infants. Therefore, in this study the investigators aimed to examine the effects of feeding temperature and the possible morbidities.

NCT ID: NCT03552510 Completed - Preterm Infant Clinical Trials

Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility

OPAMM
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Mother's milk does not come in contact with the oropharyngeal pouch of preterm infants during gavage feeding. We hypothesized that stimulation of the oropharyngeal pouch using small amount of the mother's milk 5 minutes before initiation of regular gavage feeding will increase the level of GIT hormones.

NCT ID: NCT02971566 Completed - Clinical trials for Placental Insufficiency

Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.

AREDF-SO
Start date: February 2013
Phase: N/A
Study type: Observational

Antenatal absent or reversed end-diastolic flow (AREDF) velocity through the umbilical arteries places preterm infants at significant risk for developing gastrointestinal complications, such as feeding intolerance, necrotizing enterocolitis or spontaneous intestinal perforation. Due to the fear of the aforementioned conditions, the establishment of adequate enteral feeds is frequently hampered in this population. Previous postnatal Doppler studies have shown that AREDF preterm infants who later developed feeding intolerance have a decreased blood flow velocity in the superior mesenteric artery in response to the first enteral feed; to date, however, it is not known whether this hemodynamic impairment persists over time, or if it is associated with reduced splanchnic oxygenation and perfusion, monitored by Near-infrared spectroscopy (NIRS). This observational prospective study aims: - to assess the patterns of abdominal oxygenation and perfusion in response to enteral feeds in AREDF preterm infants at different phases of enteral feeding establishment; - to evaluate a possible correlation with the development of gastrointestinal complications.