Vaginal Estrogen for the Treatment of Faecal Incontinence in Women

Fecal Incontinence Clinical Trial

Official title: A Pilot Study to Examine the Efficacy of Vaginally Administered Oestradiol in the Treatment of Faecal Incontinence in Post Menopausal Women

Status Terminated

Clinical Trial Summary

This study will address the following questions:

• Does the use of oestrogen inserted vaginally with an applicator, help with the symptoms of faecal (bowel) incontinence in women who are past the age of menopause?

• Do women find it easy to use?

• Is the treatment safe for the womb lining?

• Is there any systemic absorption of the treatment?

Clinical Trial Description

Faecal incontinence affects about 5% of women, the most common cause is often cited by women as obstetric trauma. However in clinical practice many women report that their symptoms of faecal incontinence begin around the same time as menopause. A community survey examining the prevalence of faecal incontinence in menopausal women is in progress. If a correlation is found between the onset of menopause and the development of faecal incontinence, further investigation of effective treatment will be indicated.

The investigators want to investigate whether vaginally administered oestradiol can alleviate or improve symptoms in women who have faecal incontinence after the menopause. This is a pilot study. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Fecal Incontinence

• NCT number: NCT00307775
• Study type: Interventional
• Source: London North West Healthcare NHS Trust
• Status: Terminated
• Phase: N/A
• Start date: March 2006
• Completion date: October 2011