Fatty Liver Disease Clinical Trial
Official title:
Prevalence of Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Among Nurses in a Single Tertiary Care Centre and the Role of Intermittent Fasting in Improving Hepatic Steatosis
This study consists of 2 parts: Part 1: a cross-sectional study, looking at the prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) among nurses in Hospital Canselor Tuanku Muhriz (HCTM). Part 2: a randomized controlled trial of intermittent fasting with MAFLD subjects.
The investigators aim to screen at least 350 participants for fibroscan-detected fatty liver. Baseline anthropometric data will be taken. Questionnaires on dietary habits - Foof Frequency Questionnaire (FFQ) and exercise habits - International Physical Activity Questionnaire (IPAQ) will be done. Approximately 100 participants who have fatty liver from Part 1 study, will be enrolled and randomized into Part 2. The intervention group will undergo intermittent fasting (3 fasting day:4 non-fasting days) while the control group will continue the usual standard care, for 8 weeks. Measurements pre- and post-intervention include Fibroscan measurement, blood LiverFASt, anthropometric data, and exercise habit (IPAQ). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05881005 -
NAC- NAFLD And Cushing
|
N/A | |
| Recruiting |
NCT05220956 -
Impact of Time-restricted Feeding in NAFLD
|
N/A | |
| Enrolling by invitation |
NCT04066608 -
Prevalence of Advanced Fibrosis in Patients Living With HIV
|
||
| Recruiting |
NCT04302051 -
Assessment of Fatty Liver With Thermo-acoustic Device
|
||
| Recruiting |
NCT04496895 -
The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults
|
N/A | |
| Active, not recruiting |
NCT05898841 -
Study to Evaluate the Efficacy and Safety of a Rilpivarine-based Antiretroviral Tratment Regimen in HIV- Infected Patients With Liver Metabolic Disease Who Maintain Udetectable HIV Viral Load
|
Phase 4 | |
| Not yet recruiting |
NCT06302049 -
Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis
|
Phase 1/Phase 2 | |
| Completed |
NCT05764811 -
SGLT-2 Inhibitor Effects on Cardiac and Hepatic Metabolic Profiles for the Diabetes Patients Combined With Obesity
|
N/A | |
| Active, not recruiting |
NCT05076058 -
Effects of Tablets of Silybum Marianum, Pueraria Lobate and Salvia Miltiorrhiza on Fatty Liver
|
N/A | |
| Recruiting |
NCT05421572 -
Epidemiological Survey on Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)
|
||
| Completed |
NCT04283942 -
Effect of Intermittent Calorie Restriction on MASLD Patients With Abnormal Glucose Metabolism
|
N/A | |
| Completed |
NCT01016418 -
Bovine Colostrum for Patients With Non Alcoholic Fatty Liver Disease
|
Phase 1/Phase 2 | |
| Terminated |
NCT04175392 -
Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis
|
Phase 1/Phase 2 | |
| Not yet recruiting |
NCT04191044 -
Portal Hypertension in Non-alcoholic Fatty Liver Disease: Association With Cardiovascular Risk and Identification of Non-invasive Biomarkers (THESIS)
|
||
| Not yet recruiting |
NCT06071923 -
Effect of Thyroid Disorders in Liver Diseases
|
||
| Recruiting |
NCT04525833 -
Liver Disease and Other Systemic Diseases
|
||
| Not yet recruiting |
NCT05966025 -
Potential Benefits of Itopride in the Management of Patients With Metabolic Associated Fatty Liver Disease (MAFLD)
|
Phase 2 | |
| Completed |
NCT04844450 -
A Single and Multiple Ascending Dose Study of Subcutaneously Administered JNJ-75220795
|
Phase 1 | |
| Completed |
NCT04367012 -
Fatty Liver Among Employees at Banha University
|
||
| Completed |
NCT05694923 -
Effect of Sodium Glucose Cotransporter Inhibitors on Non Diabetic Fatty Liver Disease Patients
|
N/A |