Fatigue Clinical Trial
Official title:
The Acute Effects of Fitness Drink Formulas Containing 100 mg and 140 mg of Caffeine on Energy Expenditure and Fat Metabolism in Healthy Adults
Verified date | June 2020 |
Source | University of Central Florida |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this investigation was to examine the acute effects of consuming two different fitness drink formulas on the physiological response at rest and to exercise in healthy men and women.
Status | Completed |
Enrollment | 56 |
Est. completion date | November 28, 2018 |
Est. primary completion date | November 28, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Young adult men and women between the ages of 18 and 35 years old. - Participant is deemed by the investigator to be healthy and free of any physical limitations determined by physical activity readiness questionnaire (PAR-Q+) and medical and activity history questionnaire (MHQ). - Participants will be required to be recreationally-active (defined according to American College of Sports Medicine standards of at least 150 minutes exercise per week and verified by information provided in the MHQ). - Participant is willing to abstain from dietary supplementation throughout the duration of the study as indicated in the Informed Consent. - Participant understands the study procedures and signs forms providing informed consent to participate in the study. Exclusion Criteria: - Inability to perform physical exercise, as determined by the PAR-Q+. - Any "Yes" response in the PAR-Q+. - History of hypertension, metabolic, hepatorenal, musculoskeletal, autoimmune or neurological disease, as determined by the MHQ. - Regular consumption of greater than 250 mg per day of caffeine - Currently taking thyroid, antihyperlipidemic, hypoglycemic, anti-hypertensive or androgenic medications. - Taking any other nutritional supplement or performance-enhancing drug (determined from MHQ) that may interfere with the outcome variables of the study. - Pregnancy (determined from MHQ). |
Country | Name | City | State |
---|---|---|---|
United States | Kinesiology Laboratories | Orlando | Florida |
Lead Sponsor | Collaborator |
---|---|
University of Central Florida | Celsius Holdings, Inc. |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in resting energy expenditure/substrate oxidation | Estimates from gas exchange analysis via indirect calorimetry | Baseline, 30, 60, and 90 min post-ingestion | |
Primary | Change in energy expenditure/substrate oxidation in response to exercise | Estimates from gas exchange analysis via indirect calorimetry | >90 min post-ingestion (pre/peri/post maximal graded exercise test) | |
Primary | Change in resting serum glycerol | Obtained from blood draw of the superficial forearm vein | Baseline, 30, 60, and 90 min post-ingestion | |
Primary | Change in oxygen consumption/carbon dioxide production in response to exercise | Estimates from gas exchange analysis via indirect calorimetry | >90 min post-ingestion (pre/peri/post maximal graded exercise test) | |
Primary | Change in resting minute ventilation | Estimates from gas exchange analysis via indirect calorimetry | Baseline, 30, 60, and 90 min post-ingestion | |
Primary | Change in minute ventilation in response to exercise | Estimates from gas exchange analysis via indirect calorimetry | >90 min post-ingestion (pre/peri/post maximal graded exercise test) | |
Secondary | Change in Automated Neuropsychological Assessment Metrics (ANAM) screening | Measures from mood scale, go/no go test, Stroop test | Baseline, 30, 60, and 90 min post-ingestion | |
Secondary | Change in resting blood pressure response | Measured via automated blood pressure monitor | Baseline, 30, 60, and 90 min post-ingestion | |
Secondary | Change in resting heart rate/heart rate variability | Measured via chest-based heart rate monitor | Baseline, 30, 60, and 90 min post-ingestion | |
Secondary | Change in heart rate/heart rate variability in response to exercise | Measured via chest-based heart rate monitor | >90 min post-ingestion (pre/peri/post maximal graded exercise test) | |
Secondary | Change in power output | Obtained via cycle ergometer during the maximal graded exercise test | >90 min post-ingestion |
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