Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task

Fatigue Clinical Trial

Official title:

Sodium Bicarbonate Supplementation Promotes Changes in Performance, Muscle Activity and Strength of Individuals Trained During the Performance of Intermittent and Intense Task? Randomized, Double-blind, Crossover Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03837886
• Other study ID #: FP001
• Status: Not yet recruiting
• Phase: N/A
• Start date: October 20, 2019
• Est. completion date: November 30, 2019

Study information

• Verified date: October 2019
• Source: University of Nove de Julho
• Contact: Marcelo M Kalytczak, PhD
• Phone: 55 11 981595139
• Email: marcelomkal[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 12
• Est. completion date: November 30, 2019
• Est. primary completion date: October 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 42 Years

Eligibility

Inclusion Criteria:

• resistance trained men (minimum 12 moths resistance training experience)

Exclusion Criteria:

• diabetes mellitus;

• respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders;

• acid-base balance disorder;

• continuous use of some type of medication;

• use of high-protein supplementation and creatine supplementation;

• users of anabolic steroids.

Related Conditions & MeSH terms

• Alkalosis
• Alkalosis, Metabolic
• Electromyography
• Fatigue
• Sodium Bicarbonate

Intervention

Dietary Supplement:
• Sodium bicarbonate
The subjects should ingest 0.3g.kg of sodium bicarbonate 90 minutes before the beginning of the protocol task.
• Calcium carbonate
The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate

Locations

Country	Name	City	State
Brazil	Nove de Julho University	São Paulo

Sponsors (2)

Lead Sponsor	Collaborator
University of Nove de Julho	Marcelo Martins Kalytczak

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment	The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.	60 minutes
Primary	Peak torque assessed with isokinetic dynamometer equipment	The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.	60 minutes
Secondary	Lactate assessed with portable lactometer	The lactate quantification will be performed before and after the test session characterized by the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with an interval of 1 minute between sets in an isokinetic dynamometer.	15 seconds