Fatigue Clinical Trial
Official title:
Anti-fatigue Effect of Korean Red Ginseng in Patients With Non-alcoholic Hepatitis
Background: Korea red ginseng (KRG) has anti-carcinogenic activity, anti-oxidant activity,
and cancer related anti-fatigue.
Methods: Seventy five patients with non-alcoholic hepatitis were prospectively randomized to
receive 3 weeks of KRG or placebo. Liver function test, pro-inflammatory cytokines,
adiponectin, fatigue severity scale, and antioxidant activity were check and compared.
Fatigue Severity Scale
We used to be KRUPP's fatigue severity scale. The survey has nine questions as following:
(1) my motivation is lower, when I am fatigued (2) exercise brings on my fatigue (3) I am
easily fatigued (4) fatigue interferes with my physical functioning (5) fatigue causes
frequent problems for me (6) my fatigue prevents sustained physical functioning (7) fatigue
interferes with carrying out certain duties and responsibilities (8) fatigue is among my 3
most disabling symptoms (9) fatigue interferes with my work, family, or social life. All
subjects scored each question on a 7-point scale (1 = strongly disagree to 4 = neither
disagree nor agree to 7 = strongly agree). All fatigue severity scale calculated and
collected by one research nurse (C.W.K) in the Department of Internal Medicine.
;
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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