Fatigue Clinical Trial - Use of Armodafinil for Fatigue in Sarcoidosis

Status Completed

Clinical Trial Summary

To determine the effect of Armodafinil (Nuvigil) on fatigue and sleep in sarcoidosis.

Clinical Trial Description

The study will be divided into two halves. Patients will receive either drug or placebo in the first half. Patients receiving active drug will be started at one dose and it can be increased at the second visit. Those patients randomized to placebo will also have their dose adjusted by the investigating physician. The physicians will be blinded as to whether the patient is receiving drug or placebo. In the second half of the study, patients will receive the opposite treatment.

Patients will have complete detailed questionnaires regarding their fatigue, sleepiness, and overall quality of life.

They will have sleep studies done at the start and after each half of the study to determine the effect of therapy on sleepiness. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00555347
Study type	Interventional
Source	University of Cincinnati
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	October 2007
Completion date	August 2011

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04959214` - The Effect Of Progressıve Relaxatıon Exercıses	N/A
Recruiting	`NCT04984226` - Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD	Phase 2
Completed	`NCT04531891` - Utility and Validity of a High-intensity, Intermittent Exercise Protocol	N/A
Active, not recruiting	`NCT05006976` - A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study	N/A
Completed	`NCT04960865` - Kinesio Taping and Calf Muscle Fatigue	N/A
Completed	`NCT02948283` - Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia	Phase 1
Completed	`NCT06421233` - The Effect of Endorphin Massage Applied to Postpartum Women on Anxiety and Fatigue Levels	N/A
Active, not recruiting	`NCT05344183` - Immediate and Short-term Effects of Low-level Laser	N/A
Completed	`NCT04716049` - Effectiveness of Recovery Protocols in Elite Professional Young Soccer Players	N/A
Completed	`NCT00060398` - Epoetin Alfa With or Without Dexamethasone in Treating Fatigue and Anemia in Patients With Hormone-Refractory Prostate Cancer	Phase 3
Recruiting	`NCT05241405` - Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast Cancer	N/A
Active, not recruiting	`NCT06074627` - Radicle Energy2: A Study of Health and Wellness Products on Fatigue and Other Health Outcomes	N/A
Completed	`NCT03943212` - The Effect of Blood Flow Rate on Dialysis Recovery Time in Patients Undergoing Maintenance Hemodialysis	N/A
Recruiting	`NCT05567653` - Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers	N/A
Active, not recruiting	`NCT05636696` - COMPANION: A Couple Intervention Targeting Cancer-related Fatigue	N/A
Not yet recruiting	`NCT05863897` - e-COGRAT: A Blended eHealth Intervention for Fatigue Following Acquired Brain Injury	N/A
Not yet recruiting	`NCT05002894` - Effect of Pilates Exercises On Fatigue In Post Menopausal Women	N/A
Recruiting	`NCT04091789` - Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea	Phase 2
Completed	`NCT02911649` - Reducing Sedentary Behaviour With Technology	N/A
Completed	`NCT03216616` - Guided Self-Management Intervention Targeting Fatigue in Rheumatic Inflammatory Diseases	N/A