Fat Embolism Syndrome Clinical Trial
Official title:
Incidence of Fat Embolism With Computer Assisted Total Knee Arthroplasty
The study to determine the if the incidence of Fat Embolism is decreased using Computer Assisted technology when performing a Total Knee Arthroplasty.
Computer assisted total knee arthroplasty is at its inception currently. There are many
unknowns about this specific technique, particularly when it comes down to fat embolism
syndrome. There is a high incidence of fat embolism during total knee arthroplasty as seen
both by echocariography as well as sampling of right atrial blood. During a jig-based, or
traditional, total knee arthroplasty, a rod is placed inside the femur, and sometimes the
tibia as well. Intrusumentations of the medullary canal is known to cause fat embolism. Fat
embolism is a syndrome which can produce post-operative confusion, hypoxemia, all the way to
post-op and intra-operative death.
Computer assisted total knee arthroplasty does not use intramedullary jigs. It is presumed
that by not instrumenting the medullary canal, the rate of fat embolism will be
significantly reduced.
Fifty patient s will be studied while they are having a computer assisted total knee
arthoplasty. A PICC line will be placed in their arm by an interventional radiologist
pre-operatively. This PICC line will be thread into the right atrium. Right atrial blood
will be sent to pathology every 10 minutes during the 60 to 90 minute procedure and at
intervals post-op. The right atrial blood will be stained for bone marrow elements.
This study is to presumed to show yet another benefit of computer assisted surgery.
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Observational Model: Case-Only