Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)

Status Recruiting

Clinical Trial Summary

Background and study aim The relative risks of duodenal adenocarcinoma and ampullary carcinoma in Familial Adenomatous Polyposis (FAP) have been estimated 100 to 330 times higher than in general population. However risk factors, including a genotype-phenotype association for duodenal cancer in FAP has not been fully understood. The aim of this study is to determine risk factors associated with the development of advanced duodenal polyposis and ampullary adenomas in colectomized patients with FAP.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02656134
Study type	Observational [Patient Registry]
Source	University of Sao Paulo
Contact	Marianny Sulbaran, MD
Phone	5511 948526841
Email	mariannysulbaran@gmail.com
Status	Recruiting
Phase	N/A
Start date	March 2015
Completion date	December 2016

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05630794` - Testing ONC201 to Prevent Colorectal Cancer	Phase 1
Completed	`NCT02961374` - Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer	Phase 2
Completed	`NCT01483144` - Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)	Phase 3
Completed	`NCT00641147` - Curcumin in Treating Patients With Familial Adenomatous Polyposis	Phase 2
Recruiting	`NCT03471403` - Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
Not yet recruiting	`NCT04531930` - Colorectal Adenoma Canceration in FAP
Recruiting	`NCT04678011` - A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
Recruiting	`NCT04677998` - A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
Completed	`NCT00927485` - Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)	N/A
Recruiting	`NCT00253812` - Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy	N/A
Withdrawn	`NCT00248053` - Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients	Phase 2
Recruiting	`NCT02012699` - Integrated Cancer Repository for Cancer Research
Completed	`NCT04674228` - Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01
Completed	`NCT01656746` - Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease	N/A
Completed	`NCT00808743` - Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis	Phase 2/Phase 3
Active, not recruiting	`NCT03847636` - CryoBalloon Ablation for Treatment of Duodenal Adenomas	N/A
Not yet recruiting	`NCT05112822` - Testing Obeticholic Acid (OCA) for Familial Adenomatous Polyposis (FAP)	Phase 1
Withdrawn	`NCT01245816` - A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)	Phase 3
Recruiting	`NCT04709445` - Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses	N/A
Enrolling by invitation	`NCT05402891` - The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis	Phase 2