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Eye Neoplasms clinical trials

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NCT ID: NCT02909517 Recruiting - Ocular Melanoma Clinical Trials

The Role of Inflammation in Ocular Tumours

Start date: March 2016
Phase:
Study type: Observational

This prospective, non-therapeutic study will determine whether a novel imaging technique can identify presumptive tumour associated macrophages (TAMs) in patients with ocular tumours. The investigators will evaluate 5 groups: 1. Choroidal nevus 2. Choroidal indeterminate melanocytic lesion 3. Choroidal melanoma 4. Suspected metastatic tumour (ie, primary tumour elsewhere) 5. Locally treated ocular tumours

NCT ID: NCT02704715 Recruiting - Postoperative Pain Clinical Trials

Postoperative Pain in Orbital Disease and Ocular Tumor

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the postoperative pain after general anesthesia of orbital diseases and ocular tumor patients.

NCT ID: NCT01653080 Active, not recruiting - Eye Cancer Clinical Trials

MRI in Diagnosing Solid Tumors of the Eye and Orbit

Start date: May 18, 2006
Phase: N/A
Study type: Interventional

This study is being done due to a new imaging method that may help others in the future to improve evaluation of diseases in the eye and eye socket and to help make a decision concerning best treatment of the disease. Previous studies suggests that dynamic contrast enhanced MRI is ideally suited to show small structures in the eye and eye socket as well as to provide information about the eye socket such as blood circulation. This research may also provide information about the likelihood of the tumor spreading from the eye into other organs as well as correlate the study images with all other clinical imaging

NCT ID: NCT00601744 Completed - Eye Cancer Clinical Trials

Social-Psychological Aspects of Orbital Exenteration

Start date: January 2008
Phase: N/A
Study type: Observational

The goal of this research study is to learn about the social and emotional factors that may affect the quality of life of patients with cancer of the eye or eye area who have had their facial appearance changed due to an orbital exenteration.

NCT ID: NCT00111046 Active, not recruiting - Melanoma Clinical Trials

Pain Relief - Tramadol Versus Ibuprofen

Start date: February 2001
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.

NCT ID: NCT00020267 Completed - Breast Cancer Clinical Trials

Vaccine Therapy in Treating Patients With Metastatic Cancer

Start date: July 2000
Phase: Phase 1
Study type: Interventional

RATIONALE: Vaccines made from a peptide may make the body build an immune response and kill tumor cells. PURPOSE: Randomized phase I trial to study the effectiveness of vaccine therapy in treating patients who have metastatic cancer that has not responded to previous therapy.

NCT ID: NCT00017147 Completed - Clinical trials for Malignant Neoplasms of Eye, Brain and Other Parts of Central Nervous System

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Start date: September 2001
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. O6-benzylguanine may help carmustine kill more tumor cells by making tumor cells more sensitive to the drug. It is not yet known whether radiation therapy and carmustine are more effective with or without O6-benzylguanine. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus carmustine with or without O6-benzylguanine in treating patients who have newly diagnosed glioblastoma multiforme or gliosarcoma.