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Clinical Trial Summary

To evaluate azithromycin tear concentrations after instillation of one drop of one of the three T1225 concentrations (0.5%, 1% and 1.5%) and to evaluate the ocular safety.


Clinical Trial Description

The aim of the present study was to compare azithromycin tear ocular concentrations after a single instillation of three different T1225 concentrations in order to determine early azithromycin tear concentration and to assess the T1225 concentration, which allowed having the higher azithromycin tear concentration, 24 hours after a single instillation. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00356850
Study type Interventional
Source Laboratoires Thea
Contact
Status Completed
Phase Phase 1
Start date May 2002
Completion date June 2002

See also
  Status Clinical Trial Phase
Completed NCT00324168 - Steroids for Corneal Ulcers Trial Phase 4
Completed NCT00357383 - Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers Phase 1
Completed NCT00357292 - Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers Phase 1
Completed NCT00356772 - Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers Phase 1
Completed NCT00357539 - Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers Phase 1
Recruiting NCT04981860 - Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine Phase 4