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Eye Diseases clinical trials

View clinical trials related to Eye Diseases.

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NCT ID: NCT00911924 Completed - Glaucoma Clinical Trials

A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma

SY
Start date: May 2009
Phase: Phase 4
Study type: Interventional

Prospective, unmasked, evaluation of the iStent in patients that have primary open-angle glaucoma (OAG). Stent implantation in one eye will be used for analysis, with medication added at 6 months, as required.

NCT ID: NCT00877032 Completed - Clinical trials for Macular Degeneration

Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration

Start date: April 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of RN6G in patients with dry, age-related macular degeneration.

NCT ID: NCT00848198 Enrolling by invitation - Dry Eye Disease Clinical Trials

TearLab Core Validation Study

CVS
Start date: February 2009
Phase: N/A
Study type: Observational

This is a global study of tear osmolarity using the OcuSense TearLab technology to compare tear samples of age and sex-matched normals with those with Dry Eye Disease (DED). Diagnosis of DED subjects will be established using objective and subjective tests. Positive responses to 3 out of 6 defined criteria determine subjects with DED. DED subjects will be further categorized by severity, using results from the objective and subjective tests. Subjects will be assessed at a single visit.

NCT ID: NCT00831662 Completed - Dry Eye Disease Clinical Trials

The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637)

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the safety and efficacy of diquafosol tetrasodium ophthalmic solution, 2% vs. placebo, in subjects with dry eye disease.

NCT ID: NCT00827255 Completed - Dry Eye Disease Clinical Trials

Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05%

Start date: January 2009
Phase:
Study type: Observational

The objective of this retrospective chart review is to evaluate the patient characteristics, treatment variations and efficacy of a second trial of Cyclosporine Ophthalmic Emulsion 0.05% therapy in chronic dry eye patients who were initially treated with Cyclosporine Ophthalmic Emulsion 0.05% but discontinued use after less than 12 weeks of treatment.

NCT ID: NCT00811512 Completed - Clinical trials for Eye Diseases, Hereditary

Fundus Changes in the Microphthalmy Eyes

Start date: May 2007
Phase: N/A
Study type: Observational

The goal is to describe the fundamental aspects of fundoscopic eye in patients with microphthalmia

NCT ID: NCT00809003 Completed - Dry Eye Clinical Trials

Assessment of Inflammatory and Functional Changes in the Ocular Surface Associated With Dry Eye Disease

JADE
Start date: September 2007
Phase: N/A
Study type: Observational

This project will examine the similarities and differences of the ocular surface and tear film in patients with Sjogren's syndrome related to dry eye, severe dry eye and those who do not have dry eye. This knowledge will help clinicians understand the processes that create these dry eye conditions and will strengthen the treatment and management strategies that will be used. The subjects will participate in a series of dry eye tests that they have already experienced in clinic, along with the gathering of tear samples and surface cells. These tissues will then be analyzed at a distant site.

NCT ID: NCT00799682 Completed - Dry Eye Disease Clinical Trials

Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z®

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if there is a difference in the ocular signs and symptoms of subjects' eyes using Xalatan® 0.005% versus Travatan Z® 0.004% based on the outcome of subject assessment and clinical assessment in patients with Ocular Hypertension or Glaucoma with mild to moderate dry eye at baseline in accordance with the Oxford Grading Scale.

NCT ID: NCT00760045 Completed - Dry Eye Disease Clinical Trials

Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of the study is to observe lacrimal fluid condition (tear film break-up time) chronologically after a single dose of AL-43546 ophthalmic products(0.15%, 0.25% and vehicle)and 0.1% sodium hyaluronate ophthalmic solution and compare lacrimal fluid retention time between them.

NCT ID: NCT00758784 Completed - Dry Eye Disease Clinical Trials

Safety and Efficacy of an Ophthalmic Solution in Dry Eye Disease

Start date: August 13, 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of an ophthalmic solution in dry eye disease.