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Eye Diseases clinical trials

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NCT ID: NCT04970329 Not yet recruiting - Dry Eye Disease Clinical Trials

Corneal Thickness Changes in Patient Undergoing Dry Eye Managment

Start date: July 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to the determine effect of dry eye and to compare the effect of artificial tears on central and peripheral corneal thickness.

NCT ID: NCT04965974 Not yet recruiting - Dry Eye Disease Clinical Trials

Efficacy of Blue Wavelength in Managing Dry Eye

Start date: July 2021
Phase: N/A
Study type: Interventional

The study is conducted to evaluate the efficacy of digital blue light blocking filter in improvement of clinical indices of dry eye and ocular symptoms related to dry eye. Introduction: Dry eye disease is a multifactorial disease of the ocular surface caused by loss of tear film homeostasis resulting damage to the ocular surface and neurosensory abnormalities.

NCT ID: NCT04960696 Completed - Dry Eye Clinical Trials

Effect on Ocular Surface Symptoms of Online Education

Start date: April 14, 2021
Phase:
Study type: Observational [Patient Registry]

retrospective, observational study.

NCT ID: NCT04946721 Recruiting - Dry Eye Disease Clinical Trials

2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD

Start date: April 27, 2022
Phase:
Study type: Observational

Evaluate and study the immunologic changes to the ocular surface in cancer patients.

NCT ID: NCT04945772 Completed - Clinical trials for Retinitis Pigmentosa

Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]

RESTORE
Start date: July 13, 2021
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the safety and efficacy of a single intravitreal injection of virally-carried Multi-Characteristic Opsin (MCO-010).

NCT ID: NCT04936854 Recruiting - Clinical trials for Thyroid-Associated Ophthalmopathy

Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Start date: January 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Sirolimus is more effective and burdened with less side effects than conventional treatment with corticosteroids in patients with active thyroid eye disease.

NCT ID: NCT04931186 Completed - Eye Diseases Clinical Trials

Nasolacrimal Duct Obstruction

Start date: July 3, 2018
Phase:
Study type: Observational

1.1 Background Obstructions of the lacrimal drainage system can be differentiated based on anatomical location or severity. But also, differentiating between congenital and acquired nasolacrimal duct obstruction (NLDO) is possible. The incidence of congenital NLDO (CNLOD) has been shown to be approximately 20%. Most of the cases undergo spontaneous remission, as the ductus nasolacrimalis may open spontaneously. About 2-12% display a symptomatic course. 2. S: 290; 3; 4, 5 Acquired NLDO may occur during childhood and adulthood. The incidence of symptomatic acquired NLDO is around 30 cases per 100.000 people in an US-based cohort study. S: 293; 30 Two major anatomical closure sites have been described, which are on the one hand located at the between the punctum and canaliculus, and on the other hand located after the lacrimal sac. 1. S. ; 2. S: 293 1.2 Aim of this study The aim of this study is to assess the success rates for different types of primary tear duct surgery, performed from 2013 - 2017 at the department of Ophthalmology and Optometry, Medical University of Vienna. Treatment success was defined as the absence of clinical signs of lacrimal drainage system obstruction (epiphora, increased tear leak, mucous discharge) and without the need for re-intervention. It is further investigated whether the type of operation performed or whether the silicone tube used influence success rates. 1.3 Methods A retrospective chart analysis of all patients - independent of the underlying pathology - undergoing surgery of the lacrimal drainage system between 1st of January 2013 and 31st December 2017. Success rates and patient profiles will be analyzed not only for all patients, but also for subgroups based on the underlying pathology and operation performed.

NCT ID: NCT04927468 Not yet recruiting - Clinical trials for Graves Ophthalmopathy

Supramaximal Rectus Recession for Strabismus in Grave's Ophthalmopathy

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate supramaximal rectus recession for strabismus in Grave's Ophthalmopathy

NCT ID: NCT04926714 Recruiting - Eye Diseases Clinical Trials

Ophthalmologic Evaluation of Patients With Obesity and Metabolic Syndrome Before and After Bariatric Surgery

Start date: May 17, 2021
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to investigate the pathogenic role of obesity on blinding eye diseases in a population of severely obese patients with no history of eye diseases, and to verify whether weight loss induced by bariatric surgery may have a protective effect.

NCT ID: NCT04919694 Not yet recruiting - Clinical trials for Thyroid Associated Ophthalmopathy

Combination of Orbital Compression Surgery and Strabismus Surgery for Thyroid Associated Ophthalmopathy

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether combination of orbital compression surgery with strabismus surgery is better than strabismus surgery after orbital compression surgery in the treatment of moderate-to-severe thyroid associated ophthalmopathy