Images in Extracranial Artery Stenosis

Extracranial Atherosclerosis Clinical Trial

Official title:

The Differences in Images of Vertebral Artery Stenosis and Carotid Artery Stenosis Pre- and Post-Percutaneous Transluminal Angioplasty and the Gene Expression Patterns in Peripheral White Blood Cells

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00173927
• Other study ID #: 9261701156
• Secondary ID: NTUH 94N04
• Status: Recruiting
• Phase: N/A
• First received: September 12, 2005
• Last updated: October 29, 2007
• Start date: March 2004

Study information

• Verified date: September 2005
• Source: National Taiwan University Hospital
• Contact: Hsien-Li Kao, MD
• Phone: 886-2-2312-3456
• Email: hsienli_kao[@]yahoo.com
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

The goals of this trial are:

1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.

2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 30 Years to 90 Years

Eligibility

Inclusion Criteria:

• Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

Exclusion Criteria:

• Acute systemic illness

• Creatinine > 3 mg/dl

• Unable to tolerate the tests (including MRI and PET/computed tomography [CT] scans)

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Atherosclerosis
• Extracranial Atherosclerosis

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan,