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Clinical Trial Summary

The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to be improved by chronic or acute increases in physical activity. Both of these have been shown to be impaired to acute bouts of inactivity in young populations; however the impact of acute inactivity in older adults is less understood. In this proposal the investigators will examine 1)how quickly impairments in glycemic control occur to acute physical inactivity in older adults who exercise, 2) how quickly impairments in endothelial function occur to acute inactivity in older adults who exercise, and 3) whether 3 days of a return to exercise restores these responses.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05468255
Study type Interventional
Source Old Dominion University
Contact Leryn Reynolds
Phone 757-683-4974
Email lreynold@odu.edu
Status Recruiting
Phase N/A
Start date July 25, 2022
Completion date April 1, 2025

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