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Clinical Trial Summary

The purpose of this study is to evaluate the investigational drug AMXT 1501 (a pill taken by mouth) in combination with the drug difluoromethylornithine (DFMO) for infusion administered intravenously (IV; a liquid that continuously goes into your body through a tube that has been placed during a surgery into one of your veins). An investigational drug is one that has not been approved by the U.S. Food & Drug Administration (FDA), or any other regulatory authorities around the world for use alone or in combination with any drug, for the condition or illness it is being used to treat. The goals of this part of the study are: - Establish a recommended dose of AMXT 1501 in combination with DFMO for infusion - Test the safety and tolerability of AMXT 1501 in combination with DFMO for infusion in patients with cancer - To determine the activity of study treatments chosen based on: - How each subject responds to the study treatment - How long a subject lives without their disease returning/progressing


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06465199
Study type Interventional
Source Milton S. Hershey Medical Center
Contact BCC Enroll
Phone 717-531-0003
Email BCCEnroll@pennstatehealth.psu.edu
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date July 2024
Completion date July 2034

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