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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03734042
Other study ID # PRPF
Secondary ID
Status Completed
Phase Phase 4
First received
Last updated
Start date December 1, 2018
Est. completion date October 31, 2021

Study information

Verified date November 2021
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

All patients prepared to thawed embryo transfer were classified into 2 groups one group will receive platelet rich plasma (PRP) infusion intrauterine and the other group will not receive platelet rich plasma (PRP) infusion


Description:

Patients candidates for Thawed embryo transfer with Repeated implantation failure were recruited from 3 centers and classified into 2 groups: Group I: Will receive platelet rich plasma (PRP) intrauterine infusion at day 11 Group II: Not receiving platelet rich plasma (PRP)


Recruitment information / eligibility

Status Completed
Enrollment 102
Est. completion date October 31, 2021
Est. primary completion date October 31, 2021
Accepts healthy volunteers No
Gender Female
Age group 20 Years to 35 Years
Eligibility Inclusion Criteria: - Patients age 20-35 years - Patients with previous implantation failure - Patients with thin endometrium<7 mm Exclusion Criteria: - Patients older than 40 years - Patients with fresh embryo transfer - Patients with abnormal uterine cavity septate, or bicornuate uterus - Patients with abnormal male factor or tubal factor - Patients with abnormal embryos grade B or C. - Patients with immunological disorders as thyroidits or systemic lupus or rheumatoid arthritis

Study Design


Related Conditions & MeSH terms


Intervention

Biological:
Platelet rich plasma intrauterine infusion
platelet rich plasma will be prepared, activated then infused by Intrauterine insemination catheter intrauterine at day 11
Normal saline
Intrauterine infusion of normal saline at day 11

Locations

Country Name City State
Egypt Ayman Shehata Dawood Tanta

Sponsors (1)

Lead Sponsor Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary Endometrial thickness The increase in endometrial thickness at day of ET 8 days
Primary Pregnancy rate Number of cases who got pregnant 15 days
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