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Study of Personalized Dietary Intervention for the Control of Essential Hypertension — PCFADASH-HT  

Essential Hypertension Clinical Trial

Official title:
Randomized Controlled Trial of a Personalized Dietary Intervention Approach for the Control of Essential Hypertension

Clinical Trial Summary

An ongoing case study of psoriasis, shows reproducibly that ingestion of hydrogenated fats, and some flavourant or sweetener compounds, leads to relapse of psoriasis, and secondary food intolerances, followed by remission over a couple of months (cpcpsoriasis.blogspot.com). Hence a personalized categorical food avoidance diet averts relapse and maintains remission of psoriasis, with side benefit on blood pressure and other metabolic parameters (J Hypertension 2012; 30: e-suppl 1, poster 158). Study hypothesis: this dietary approach would improve the control of essential hypertension. A randomized controlled clinical trial is proposed to compare this dietary approach with conventional DASH-type dietary counselling. 40 study participants will be randomly assigned to either conventional or interventional dietary counselling. They will be comprehensively monitored (including gene expression studies) for two years. Outcome criteria will include blood pressure, complications of hypertension, side-benefit on comorbidity, and requirement for antihypertensive drugs.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02136264
Study type Interventional
Source University of Nigeria, Enugu Campus
Contact Nnamdi Nwosu, MB BS FWACP
Phone +2348037123803
Email dykenig@yahoo.com
Status Recruiting
Phase N/A
Start date June 2013
Completion date June 2018
View Details
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