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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03347903
Other study ID # 1164/2017
Secondary ID
Status Completed
Phase N/A
First received November 15, 2017
Last updated November 18, 2017
Start date January 1, 2014
Est. completion date May 30, 2017

Study information

Verified date November 2017
Source Medical University of Vienna
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Gastroesophageal reflux disease (GERD) is involved in the development of esophageal motility disorders like Jackhammer esophagus (JE), a novel hypercontractile condition that was associated with progression to achalasia and limited outcomes following surgical anti-reflux therapy.

This trial was designed to assess the prevalence and characteristics of JE in patients with typical symptoms of GERD and responsiveness to PPI therapy.


Description:

Jackhammer esophagus is a novel hypercontractile esophageal disorder. The investigators assess the prevalence and clinical characteristics of patients diagnosed with this disorder out of a collective of patients that are referred with symptoms of gastroesphageal reflux disease and respond to PPI. This is an observational trial.


Recruitment information / eligibility

Status Completed
Enrollment 37
Est. completion date May 30, 2017
Est. primary completion date May 30, 2017
Accepts healthy volunteers
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- Patients with symptoms of gastroesophageal reflux disease and diagnosis of Jackhammer esophagus

Exclusion Criteria:

- patients not willing to participate data or undergo screening for gastroesophageal reflux disease

Study Design


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Medical University of Vienna

Outcome

Type Measure Description Time frame Safety issue
Primary Prevalence of Jackhammer esophagus in patients referred with symptoms of gastroesophageal reflux disease All patients that are referred to our center with symptoms of gastroesophageal reflux disease routinely undergo high-resolution manometry. We assess how many patients are diagnosed with Jackhammer esophagus January 2014- May 2017
Secondary Symptom perception We assess which symptoms are perceived by the patients diagnosed with Jackhammer esophagus. All data are observed during an interview at the high-resolution manometry January 2014- May 2017
Secondary Prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus All patients that are referred to our center are evaluated for gastroesophageal reflux disease. We assess the prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus diagnosed by ambulatory pH monitoring. Januar 2014- May 2017
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