Esophageal Atresia Clinical Trial
— REGATEOfficial title:
National Register of Oesophageal Atresia
The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), sometimes associated (from 50%) of other malformations (heart, kidney, digestive ...). The current prognosis for this ailment is good. However he persists a mortality (<10%) and significant morbidity, firstly related malformations (heart, kidney, for example), and secondly with particularly difficult anatomical forms (Forms long defect) . The prevalence of this condition is estimated to be 1/2500 in 3000 live births, making an estimated ± 2,500 new cases over to 10 years in France. The current project aims to set up a national registry (Metropolitan France and Dom Tom) to measure the prevalence of esophageal atresia among live births, phenotypic characteristics, the circumstances of their diagnosis, and their initial future at short-term during the first year of life, at which time occurs the vast majority of deaths and complications in this disease.
Status | Recruiting |
Enrollment | 2500 |
Est. completion date | December 2025 |
Est. primary completion date | December 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 1 Year |
Eligibility | Inclusion Criteria: - To be born in France - To have a esophageal atresia Exclusion Criteria: - To be born abroad |
Country | Name | City | State |
---|---|---|---|
France | CHU Amiens-Picardie | Amiens | |
France | CHU d'Angers | Angers | |
France | CHRU Besançon | Besançon | |
France | CHU de Bordeaux | Bordeaux | |
France | CHRU Brest | Brest | |
France | HFME de Lyon | Bron | |
France | CHU de Caen | Caen | |
France | CHU de Clermont-Ferrand | Clermont-Ferrand | |
France | Hôpitaux Civils de Colmar | Colmar | |
France | CHI Créteil | Créteil | |
France | CHU Dijon Bourgogne | Dijon | |
France | CHU de Grenoble | La Tronche | |
France | AP-HP CHU Kremlin-Bicêtre | Le Kremlin-Bicêtre | |
France | CH Le Mans | Le Mans | |
France | CHRU,Hôpital Jeanne de Flandres | Lille | |
France | CHU de Limoges | Limoges | |
France | AP-HM La Timone | Marseille | |
France | AP-HM Nord | Marseille | |
France | CHRU de Montpellier | Montpellier | |
France | CHU de Nantes | Nantes | |
France | CHU de Nice | Nice | |
France | CHR d'Orléans | Orléans | |
France | AP-HP Armand Trousseau | Paris | |
France | AP-HP Necker-Enfants malades | Paris | |
France | AP-HP Robert-Debré | Paris | |
France | CHU de Poitiers | Poitiers | |
France | CHU de Reims | Reims | |
France | CHU de Rennes | Rennes | |
France | CHU de Rouen | Rouen | |
France | CHU Félix-Guyon | Saint Denis | La Réunion |
France | CHU de Saint-Etienne | Saint-Priest en Jarez | |
France | CHU de Strasbourg | Strasbourg | |
France | CHU de Toulouse | Toulouse | |
France | CHRU de Tours | Tours | |
France | CHU de Nancy | Vandœuvre-lès-Nancy | |
Guadeloupe | CHU de Pointe-à-Pitre | Pointe-à-Pitre | |
Martinique | CHU de Martinique | Fort-de-France |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Lille |
France, Guadeloupe, Martinique,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of esophageal atresia | 10 years | ||
Secondary | Data collection patient with esophageal atresia | Circumstances of diagnosis, modalities of follow-up and clinical management | 10 years | |
Secondary | Total number of patients with complications | 10 years | ||
Secondary | Death | 10 years |
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