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Erectile Dysfunction clinical trials

View clinical trials related to Erectile Dysfunction.

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NCT ID: NCT02413099 Completed - Clinical trials for Erectile Dysfunction

The Efficacy and Safety of New Herbal Formula (KBMSI-2) in the Treatment of Erectile Dysfunction

Start date: February 2012
Phase: Phase 4
Study type: Interventional

Background: KBMSI-2, which is the herbal formular consisted of Ginseng Radix Rubra, Dioscorea tenuipes, Cornus officinalis Sieb. Et Zucc, Lycium Chinese Mill, Curcuma logna Linn, Honey, improved the erectile function by preserving the smooth muscle content and inhibiting the fibrosis of the corpus cavernosum in STZ-induced diabetic rat model. In this study, the researchers investigated the efficacy and safety of the herbal formula (KBMSI-2) in the treatment of ED. Material and Methods: Patients were instructed to take investigational products (KBMSI-2 6g or placebo) twice a day for 8 weeks at least 1 hour after food intake. The primary efficacy variable was the change in the EF domain scores of the IIEF questionnaire from baseline. Secondary efficacy measures included change in all domain scores of the IIEF from baseline, change in question 2 and 3 of the SEP2,3, from baseline.

NCT ID: NCT02412345 Completed - Clinical trials for Erectile Dysfunction

Extracorporeal Shockwave Therapy in the Treatment for Erectile Dysfunction in Male Renal Transplant Recipients

Start date: January 2015
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine the impact of the shock wave application in renal transplant patients with diagnosis of erectile dysfunction. Secondary objectives are to assess the effects of therapy on quality of life and depression. It is expected that with the study is defined the usefulness of the therapy and the dissemination of knowledge generated for change in clinical management in renal transplant patients with erectile dysfunction.

NCT ID: NCT02398370 Completed - Clinical trials for Erectile Dysfunction

Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED

PMD-MSC-ED-01
Start date: July 2013
Phase: Phase 1
Study type: Interventional

Prospective, open-label, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of mild to moderate erectile dysfunction. Follow up visits will be conducted at 6 weeks, 3 months, 6 months, and 12 months. Subjects will be evaluated for re-injection beginning at 3 months. Eligibility is determined by the clinician based on patient reported treatment satisfaction.

NCT ID: NCT02390960 Completed - Clinical trials for Erectile Dysfunction

Phase 2a Topical Sildenafil Proof-of-Concept Study in Men With Mild to Moderate ED

Start date: March 2015
Phase: Phase 2
Study type: Interventional

This is a Phase 2a, single-dose, double-blind, placebo-controlled, 2-way crossover study in men with ED. A single 2 gram dose of SST-6006 topical cream 5% w/w (formulated to deliver 100 mg of sildenafil) or a topical placebo cream will be applied to the penile shaft and glans. There are 4 study phases: the Initial Patient Screening Phase (Visit 1, an Off Site 4-Week Run-in Period and Visit 2), the Final Patient Screening Phase (Visit 3), the SST-6006/Placebo Double-Blind Dosing Phase (Visits 4-5), and the Follow-up Phase. Primary outcomes will be be evaluated at Weeks 7 and 8 of the study

NCT ID: NCT02381912 Completed - Clinical trials for Erectile Dysfunction

Sexual Function in Patients Suspected of Non-muscle Invasive Bladder Cancer

Start date: March 2015
Phase: N/A
Study type: Observational

The purpose of the study is to investigate sexual function in patients suspected of non muscle invasive bladder cancer (NMIBC). The investigators hypothesis is that reduced sexual function is underdiagnosed in patients with non-muscle invasive bladder cancer and that active examination and treatment may worsen the sexual function.

NCT ID: NCT02344849 Completed - Clinical trials for Erectile Dysfunction

Safety of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Erectile Dysfunction

Start date: July 2015
Phase: Phase 1
Study type: Interventional

This phase I clinical trial is designed to evaluate the safety of autologous Mesenchymal Stem Cells (MSC) injected intracavernously.

NCT ID: NCT02344823 Recruiting - Clinical trials for Erectile Dysfunction

Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis

Start date: June 2012
Phase: Phase 4
Study type: Interventional

The investigators want to analyze the effect of Vardenafil on Erectile Dysfunstion and portal hemodynamics in patients with liver cirrhosis.

NCT ID: NCT02304679 Completed - Clinical trials for Erectile Dysfunction

Low Energy Shockwave Therapy for Improving Erectile Dysfunction

Shock-ED
Start date: July 1, 2015
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the change from baseline in the erectile function domain of the International Index of Erectile Function (IIEF-EF) scores in patients receiving 4 weekly treatments of shockwave therapy versus those receiving a sham treatment. The change will be evaluated at 3 months after the end of a sequence of 4 weekly treatments.

NCT ID: NCT02284659 Completed - Clinical trials for Erectile Dysfunction

Effect of Functional Electrical Stimulation on Erectile Dysfunction

Start date: November 2014
Phase: N/A
Study type: Interventional

Objective: The aim of this study is to evaluate the FES effect on erectile function in men with erectile dysfunction. Expected Results: The hypothesis is that treatment with FES decrease erectile dysfunction.

NCT ID: NCT02240823 Unknown status - Clinical trials for Delayed Graft Function

Can Fat Derived Stem Cells (SVF) be Used in the Treatment of Erectile Dysfunction After Prostatectomy

Start date: April 2014
Phase: Phase 1
Study type: Interventional

Prostate cancer is the most common cancer among Danish men, and the incidence is increasing. Studies have shown a high number needed to treat for each saved prostate cancer related death. Since the treatments incur many complications, there is a need to address these. After prostatectomy, 80% experience erectile dysfunction. Sexual life is a central part of people's identity, self-esteem and quality of life. Stem cells have generated a large amount of promising data suggesting that stem cells can alleviate erectile dysfunction, by regenerating nerves as well as endothelial and smooth muscle cells in the corpus cavernous.