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Epiretinal Membrane clinical trials

View clinical trials related to Epiretinal Membrane.

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NCT ID: NCT02691429 Completed - Clinical trials for Diabetic Retinopathy

Applicability of the Acai Fruit (Euterpe Oleracea) Dye for Chromovitrectomy in Humans

Start date: February 2016
Phase: N/A
Study type: Interventional

Our research group tested the toxicity of different dye concentrations extracted from the acai fruit using a rabbit model. The dye extracted from the acai fruit in concentrations of 10% and 25% was found to be safe for vitreoretinal surgery. This initial research represented the landmark research for testing this alternative vital dye in a clinical research in humans. The aim of the present clinical trial in humans will be to test the applicability of the acai dye in the identification of the posterior hyaloid and ILM during vitreoretinal surgery in humans.

NCT ID: NCT02628158 Completed - Epiretinal Membrane Clinical Trials

Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

Start date: April 2013
Phase: N/A
Study type: Observational

Fundus autofluorescence (FAF) at the macula originates from hyperfluorescence from retinal pigment epithelium (RPE) and blockage of hyperfluorescence by macular pigment. Investigators evaluate whether presence of FAF may correlate to the postoperative visual outcome for epiretinal membrane.

NCT ID: NCT02617147 Completed - Epiretinal Membrane Clinical Trials

Choroidal Thickness Vitrectomy

Start date: June 16, 2014
Phase:
Study type: Observational

The purpose of this study is to assess the influence of vitrectomy on changes in central choroidea and comparing the results in imaging of the choroidea with two different OCT devices. This is a prospective, open, non-randomized, observational, MPG study This study will be performed at the Department of Ophthalmology, Medical University of Vienna. 40 Patients who undergo vitrectomy will be included into this study. The investigation will help to gain new information about the effects of vitrectomy on the choroid.

NCT ID: NCT02423161 Completed - Retinal Detachment Clinical Trials

PIONEER: Intraoperative and Perioperative OCT Study

PIONEER
Start date: August 2011
Phase: N/A
Study type: Observational

OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician. Utilizing this information during surgery will allow for ophthalmic surgeons to better understand how surgical procedures impact the anatomic structure of the eye.

NCT ID: NCT02413619 Completed - Epiretinal Membrane Clinical Trials

Refractive Consequences of Epiretinal Membrane Surgery

EPIREF
Start date: May 2014
Phase: N/A
Study type: Interventional

Epiretinal membrane is treated with vitrectomy and peeling. Afterwards cataract is usually developed, which requires a cataract surgery. The aim of this study is to investigate the refractive consequences of surgery for Epiretinal membrane and cataract. Investigators investigate the sequence of surgery in patients having surgery for Epiretinal membrane and cataract in a prospective clinically randomized intervention trial. Patients are randomized to 1) start with vitrectomy, 2) start with cataract surgery, 3) combined surgery. Investigators want to find the sequence of surgery that gives the most optimal refractive result, the most stabile intraocular lens, and the minimal loss of corneal endothelial cells.

NCT ID: NCT02412059 Completed - Epiretinal Membrane Clinical Trials

Topical Use of Corticosteroid to Prevent Epiretinal Membrane Following Retinal Tear

Start date: August 2015
Phase: N/A
Study type: Interventional

In this prospective randomized controlled double blind pilot clinical study, we aim to assess whether administration of a topical corticosteroid would attenuate epiretinal membrane formation following development of retinal tears treated with laser retionpexy.

NCT ID: NCT02406430 Completed - Clinical trials for Epiretinal Membranes

Prognostic Factors in Epiretinal Membrane Surgery

Start date: April 2009
Phase: N/A
Study type: Observational

Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery. Age, duration of symptoms, and preoperative best corrected visual acuity appeared to be reliable prognostic factors. Combining these factors with analysis of the photoreceptors' inner and outer segments junction in spectral-domain optical coherence tomography provides a predictive score to estimate individual chances of good visual recovery

NCT ID: NCT02390245 Completed - Cataract Clinical Trials

Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study

Start date: September 2014
Phase: N/A
Study type: Interventional

The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye pressure measurements to improve access and utilization of eye care to detect, treat, and manage high-risk patients with previously undiagnosed glaucoma and other eye diseases. Research shows that subject failure to attend follow-up eye care appointments diminishes any previous benefits of community screenings for glaucoma. Greater adherence to follow-up visits can reduce glaucomatous blindness.

NCT ID: NCT02319655 Completed - Epiretinal Membrane Clinical Trials

Morphologic Changes After Membrane Peeling With Air Tamponade and Balanced Salt Solution

Start date: June 2014
Phase: N/A
Study type: Interventional

During the last decade optical coherence tomography (OCT) extended the possibilities for in vivo macula diagnostic and was increasingly used for pre- and post-operative imaging of retinal diseases. Spectral-domain optical coherence tomography (SD-OCT) with its increased scanning speed and image-resolution provides more detailed information of microstructures in the macula. Epiretinal membrane (ERM) is a disorder involving the posterior pole of the eyeball. It can be idiopathic or caused secondarily in various ocular conditions, such as uveitis, trauma, retinal detachment or retinal vascular diseases. In patients who suffer from loss of vision and metamorphopsia, vitrectomy and membrane peeling is usually performed to remove the ERM. Different study groups showed that intraoperative use of SD-OCT is possible. Two groups already achieved to work operation microscope integrated SD-OCT setup. Due to the high axial resolution of the SD-OCT some groups reported about an increased hyporeflective zone in the subfoveal region appearing directly after the membrane peeling procedure. It was hypothesized that this phenomenon could be an expression of surgical trauma, as this hyporeflective zone disappears in follow up OCT 10 days after surgery.

NCT ID: NCT02146144 Completed - Clinical trials for Idiopathic Epimacular Membrane

Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling)

Peeling
Start date: September 9, 2014
Phase: N/A
Study type: Interventional

The epimacular membrane (EMM) is a degenerative condition associated with age, with a variable impact on vision. Treatment is surgery based and consists of a vitrectomy followed by a peeling of the epimacular membrane using a microgripper. Peeling of the internal limiting membrane (ILM) is an adjuvant action that is now frequently practiced and which is expected to increase the success rate of EMM surgery by reducing the risk of recurrence of EMM. Although ILM peeling does not seem to have an adverse effect on visual acuity, it is not totally without consequence, it involves the risk of histological disorganization of the retina at the origin of one or several microscotomas, which are themselves responsible for a final visual discomfort. These microscotomas, resulting in the perception of somewhat black spots visible near the fixed point or the fixed image, may be highlighted by microperimetry and would be a loss of functional opportunity for the patient. In addition, recurrence of EMM, which the ILM peeling is supposed to diminish, does not alter the vision in half the patients. Furthermore, for those patients who are functionally affected by any such recurrence, a second epimacular membrane peeling surgery can be done. The main objective of this study is to compare the difference in microscotoma(s) before surgery and 6 months later, between an "active ILM peeling" group and a "no ILM peeling" group. Given the more invasive nature of ILM peeling, the investigators believe that the rate of microscotomas in these patients is higher than those without peeling.