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Clinical Trial Summary

This is a pilot, open-label, phase II study. The main objective of the study is to demonstrate that Cannabidiol (CBD), used in addition to current anti-seizure medications (ASMs) reduces the number and/or severity of motor (generalized, focal, or both) seizures in children and young adults with rare disease-associated severe epilepsy. Secondary objectives include assessment of safety and tolerability, changes in behaviour, cognition and sleep, pharmacokinetic interaction with concurrent ASMs.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05803434
Study type Interventional
Source Meyer Children's Hospital IRCCS
Contact Renzo Guerrini, MD, FRCP, FAES
Phone 00390555662573
Email renzo.guerrini@meyer.it
Status Not yet recruiting
Phase Phase 2
Start date June 1, 2023
Completion date March 1, 2025

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