Computational Neuroscience of Language Processing in the Human Brain

Status Recruiting

Clinical Trial Summary

Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.

Clinical Trial Description

The neural architecture of language is the foundation for the highest form of human interaction. Prior work has identified a network of frontal and temporal brain areas that selectively support language processing, but the precise computations that underlie our ability to extract meaning from sequences of words have remained unknown. The standard approaches in human cognitive neuroscience lack the spatial and temporal resolution necessary for precise comparisons to computational models. To bridge this gap in knowledge, neural responses to language stimuli will be collected from epileptic patients undergoing intracranial monitoring. Overall, these data will be used to identify cortical maps of different linguistic manipulations and to better understand properties of the human language network. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05222594
Study type	Interventional
Source	Massachusetts General Hospital
Contact	Evelina Fedorenko, PhD
Phone	617-258-0670
Email	evelina9@mit.edu
Status	Recruiting
Phase	N/A
Start date	April 2, 2021
Completion date	March 31, 2026

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