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Mapping Epileptic Networks Using Multimodal Imaging — CREIM  

Epilepsy in Children Clinical Trial

Official title:
Mapping Epileptic Networks Using Multimodal Imaging

Clinical Trial Summary

Currently, mapping the epileptogenic zone is based on a comprehensive preoperative assessment involving clinical, imaging and electrophysiological examinations. To reduce the need for invasive stereoelectroencephalography (SEEG) explorations, electrophysiological and imaging methods have been developed, such as resting-state functional MRI (fMRI) coupled with electroencephalogram and arterial spin-labeling perfusion MRI (ASL-MRI). It has been published that these new methods enable precise delineation of the epileptogenic zone and better preparation for surgery. The aim is to determine whether, in children with focal lesional epilepsy, the combination of ASL-MRI-EEG and resting-state fMRI-EEG enables precise identification of the epileptogenic zone to be defined by SEEG, the current reference examination.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06202976
Study type Observational
Source Imagine Institute
Contact Nathalie Boddaert, Pr
Phone +33 (0)1 44 49 51 75
Email nathalie.boddaert@aphp.fr
Status Recruiting
Phase
Start date September 14, 2017
Completion date September 13, 2030
View Details
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