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Clinical Trial Details — Status: Withdrawn

Administrative data

NCT number NCT00336154
Other study ID # 2140CTIL
Secondary ID
Status Withdrawn
Phase Phase 4
First received
Last updated

Study information

Verified date October 2020
Source Rambam Health Care Campus
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Epidermolysis Bullosa(EB) is an inherited bullous disease. Tetracycline is believed to have anti inflammatory properties. 20 patients with EB older than 13 years will be treated for 4 months with tetracycline or placebo. After one month of wash out they will be treated for additional 4 m with placebo or tetracycline. The patients will be examined each month to estimate bulla formation,rate of healing .


Description:

Epidermolysis Bullosa(EB) is an inherited bullous disease. Tetracycline is believed to have anti inflammatory properties. 20 patients with EB older than 13 years will be treated for 4 months with tetracycline or placebo. After one month of wash out they will be treated for additional 4 m with placebo or tetracycline. The patients will be examined each month to estimate bulla formation,rate of healing .


Recruitment information / eligibility

Status Withdrawn
Enrollment 0
Est. completion date
Est. primary completion date June 2006
Accepts healthy volunteers No
Gender All
Age group 13 Years to 60 Years
Eligibility Inclusion Criteria: - diagnosed as epidermolysis bullosa - not pregnant - active disease - more than 5 bulla- Exclusion Criteria: - age less than 13 - known sensitivity to tetracyclin - abnormal liver and kidney tests.

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
tetracyclin


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Rambam Health Care Campus

Outcome

Type Measure Description Time frame Safety issue
Primary no of blisters
See also
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