FeNO Hairdressers Pilot

Environmental Exposure Clinical Trial

Official title:

Fraction of Exhaled Nitric Oxide (FeNO) in an Occupational Cohort of Hairdressers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05507944
• Other study ID #: 22/16786
• Status: Completed
• Start date: September 15, 2022
• Est. completion date: November 15, 2022

Study information

• Verified date: August 2022
• Source: Oslo University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

A 5-day cohort diurnal FeNO study of exposed and unexposed to airway irritants during hair treatments and commuting.

Description:

The project aims to increase the knowledge of daily variations in FeNO with emphasis on exposure of airway irritants during hairdressing treatments in an occupational setting and commuting. Daily measurements of FeNO before and after workplace exposure in an exposed and an unexposed cohort during a workweek (Monday to Saturday) will indicate patterns of proinflammatory responses in a dose-dependent manner. These may or may not be indicative of an increased risk for airway related disease. Results may be used for further studies of occupational hygiene, airway related disease and identification of endogenous volatile organic compounds during proinflammatory responses.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: November 15, 2022
• Est. primary completion date: September 30, 2022
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• have given informed consent.

• employed as hairdressers or at Oslo University Hospital as healthcare workers.

• scheduled work for at least 3 hours daily for 5 days in the study week.

Exclusion Criteria:

• lung disease.

• active smoker.

Related Conditions & MeSH terms

• Environmental Exposure
• Occupational Exposure

Intervention

Diagnostic Test:
• FeNO measurement
Diurnal measurements before work and at 3 hours after work start.

Locations

Country	Name	City	State
Norway	Oslo University Hospital	Oslo

Sponsors (1)

Lead Sponsor	Collaborator
Oslo University Hospital

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Daily FeNO (ppb measured by Niox Vero) increase after occupational exposure.	At start of work and after 3 hours. Hardressers vs. Health care workers.	1 day.
Primary	Daily FeNO (ppb measured by Niox Vero) increase after enviromental exposure during commuting.	At start of work and after 3 hours. Subgrouped after way of commuting.	1 day.
Primary	Diurnal FeNO (ppb measured by Niox Vero) variations during a work week after occupational exposure.	At start of work and after 3 hours. Hardressers vs. Health care workers.	6 days
Primary	Diurnal FeNO (ppb measured by Niox Vero) variations during a work week after environmental exposure during commuting.	At start of work and after 3 hours. Subgrouped after way of commuting.	6 days