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Enuresis clinical trials

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NCT ID: NCT04097288 Completed - Clinical trials for Stress Urinary Incontinence

Effects of Single Dose Citalopram and Reboxetine on Urethral and Anal Closure Function on Healthy Female Subjects

Start date: September 17, 2019
Phase: Phase 1
Study type: Interventional

This study will investigate if citalopram, a selective serotonin reuptake inhibitor, is reducing the opening pressure of the urethra and possibly causing or worsening stress urinary incontinence. Reboxetine, a norepinephrine reuptake inhibitor, is known to increase urethral opening pressure through actions on adrenoceptors in Onuf´s nucleus and will act as an active control. Furthermore, this study is performed to explore the effects of reboxetine and citalopram on the opening pressure of the anal canal.

NCT ID: NCT04094753 Recruiting - Incontinence, Urge Clinical Trials

Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older People

Start date: January 1, 2014
Phase:
Study type: Observational

Urinary incontinence is an increasing medical and socio-economical problem. 44% of the elderly (>65 years) women and 28% of the elderly men suffer from unwilling urine loss. Moreover, this percentages increase with age. Incontinence is a problem with multiple physical, psychological, and financial effects. In addition incontinence has a important impact on the family and healthcare professionals surrounding the elderly. The problem of urinary incontinence is complex and multifactorial. Moreover, diagnostic guidelines are inconsistent leading to a high amount of technical interventions to diagnose and to specify the type of incontinence. Aim of this study is to create a short form of necessary technical investigations to diagnose and evaluate urinary incontinence.

NCT ID: NCT04090190 Completed - Clinical trials for Urinary Incontinence

Inflammation in Women With Urgency Urinary Incontinence Treated With Anticholinergics

Start date: October 30, 2019
Phase: Phase 4
Study type: Interventional

Urinary incontinence (UI) is a very common condition affecting women of all ages. The objective of this pilot study is to better understand the urinary microbiome and associated inflammatory markers in blood and urine in women with urgency UI. The study will assess how inflammation may affect response to standard of care anticholinergic medication treatment for urgency urinary incontinence.

NCT ID: NCT04087642 Recruiting - Clinical trials for Pelvic Organ Prolapse

CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict Postoperative de Novo Stress Urinary Incontinence (PONSUI) at the Time of Pelvic Organ Prolapse (POP) Surgery

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The CREDE pilot randomized study will compare the intraoperative Crede manoeuver (M1) to preoperative prolapse (POP) reduction cough stress test (M2) for the prediction and prevention of PONSUI. The rates of PONSUI and its effect on patient reported outcomes and quality of life will be determined among women with positive or negative tests, and those with and without concomitant anti-incontinence procedure performed. This information will help inform larger studies on the topic.

NCT ID: NCT04084340 Completed - Clinical trials for Urinary Incontinence

tDCS and Female Urinary Incontinence

Start date: November 14, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Urinary incontinence (UI) is defined as any involuntary loss of urine and can be divided into three types: urgency, stress and mixed. Pelvic floor exercises are considered the main non pharmacological choice for UI treatment. Its mechanisms are not fully understood, however there are some evidence that central mechanisms play an important role in the continence control. In this context, neuromodulatory techniques, such as transcranial direct current stimulation (tDCS), that address cortical targets has been demonstrated promising results in different health conditions. However, few studies have investigated the efficacy of adding tDCS to exercise therapies for women with UI.

NCT ID: NCT04071301 Completed - Clinical trials for Urinary Incontinence

Collection of Real-life Measurement Data for TENA SmartCare Change Indicator in Subjects With Urinary Incontinence

Start date: September 5, 2019
Phase: N/A
Study type: Interventional

This study is an explorative, open, single-arm clinical investigation to collect real-life measurement data in order to assess the mathematical algorithms involved in TENA SmartCare Change Indicator.

NCT ID: NCT04068025 Completed - Quality of Life Clinical Trials

Information, Motivation, Behavioral Skills Model on Urinary Incontinence and Quality of Life in Men

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Multiple studies have shown that education based on the IMB model is effective at bringing about health-related behavior change. The IMB model was found to be effective in developing healthy behaviors aimed at maintaining heart health, providing behavior to prevent smoking addiction, diabetes management, correct nutrition in iron deficiency anemia, and using condoms to prevent HIV. There are no studies in the literature regarding the adaptation of the IMB model to behavioral therapy in patients with OAB or urinary incontinence. To address this, there we aimed to investigate the effect of the IMB model on urinary incontinence and quality of life in men with OAB.

NCT ID: NCT04064970 Completed - Clinical trials for Urinary Incontinence

Patient Satisfaction Survey of Non-surgical Urinary Incontinence Treatment

Start date: March 14, 2019
Phase:
Study type: Observational

The purpose of this study is to identify self-reported wellness following nonsurgical treatment of stress urinary incontinence. This will be done by correlating the response of "yes" on the patient acceptable symptom state (PASS) question to responses from other questionnaires regarding urinary symptoms.

NCT ID: NCT04059653 Terminated - Clinical trials for Urinary Incontinence

Evaluation of a New Technology for the Treatment of Bladder Leakage in Women

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

Evaluation of a new technology for the treatment of bladder leakage in women. The objective is to compare quality of life and other incontinence associated outcomes between women receiving routine General Practitioner (GP) prescribed care for urinary incontinence compared with those prescribed the electrical stimulation device.

NCT ID: NCT04059133 Recruiting - Overactive Bladder Clinical Trials

The Effect of Low Intensity Extracorporeal Low Energy Shock Wave Therapy on Stress Urinary Incontinence and Overactivity Bladder

Start date: February 27, 2018
Phase: N/A
Study type: Interventional

The hypothesis of the present study is low intensity extracorporeal low energy shock wave therapy (LiESWT) can decrease inflammatory disorders, increase pelvic floor blood supply, enhanced bladder stem cell activation, Using LiESWT can decrease bladder overactivity, eliminate urinary incontinence and improve stress urinary incontinence (SUI) and overactive bladder (OAB) symptoms. Therefore improve quality of life and improve social activity.