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Enuresis clinical trials

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NCT ID: NCT06265896 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Effect of Kinesiotaping on Activation of Abdominal Muscles in Female Patients With Stress Urinary Incontinence

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate the effect of kinesiotaping on activation of abdominopelvic cavity for management of stress urinary incontinence females' patients.

NCT ID: NCT06247241 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

A Phase 2a Study To Evaluate VMB-100 In Females With Stress Urinary Incontinence

Start date: April 2024
Phase: Phase 2
Study type: Interventional

The study drug VMB-100 is an mRNA encoding for IGF-1. It is administered by injection into the urethra sphincter, and taken up by the muscle cells. The IGF-1 acts to promote muscle regeneration in the sphincter, which is expected to improve the function of the sphincter and thereby alleviate incontinence (urinary leakage).

NCT ID: NCT06111209 Not yet recruiting - Menopause Clinical Trials

The Anabolic Effect of Testosterone on Pelvic Floor Muscles

Start date: May 2024
Phase: Phase 2
Study type: Interventional

Stress urinary incontinence is the most common female pelvic floor disorder encountered in clinical practice with significant negative impact on quality of life. The prevalence of urinary incontinence increases with aging, and weakness of the pelvic floor muscles contributes to the development of stress urinary incontinence. Given that androgen receptors are expressed throughout the pelvic floor, the anabolic effects of androgens on pelvic floor muscles may provide a therapeutic option in women with stress urinary incontinence. The investigators are conducting a randomized, double-blind, placebo-controlled proof-of-concept trial in older postmenopausal women with stress urinary incontinence to assess whether testosterone therapy can increase pelvic floor muscles and improve urinary function.

NCT ID: NCT06109623 Not yet recruiting - Clinical trials for Urinary Incontinence,Stress

Correlation Between Changes in Sex Hormone Levels and Stress Urinary Incontinence in Women

Start date: November 15, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the relationship between stress urinary incontinence and endogenous steroids in women, especially its occurrence and severity with androgens and estrogens. The main questions it aims to answer are: - Association between stress urinary incontinence and endogenous steroids in women - Risk factors associated with stress urinary incontinence in women Participants will be asked to provide basic clinical information as well as results of measurements of serum steroid hormone levels. Researchers will compare Stress urinary incontinence group and control group to see if the changes of sex hormone levels were statistically significant.

NCT ID: NCT06040645 Not yet recruiting - Clinical trials for Urinary Incontinence

Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult

OUTPACE
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population. Although numerous non-surgical management strategies have proven efficacy for both stress and urge urinary incontinence, there remains a lack of appropriate UI management in the primary care setting. The goal of this multi-site cluster randomized comparative effectiveness trial is to compare the effects of two methods of nonsurgical UI care delivery - electronic consult vs. advanced practice provider (APP) co-management. These two evidence-based, practice-changing strategies are designed to improve the quality of care for an ethnically diverse population of women with UI, and, by reducing deficits in care, obtain better patient-reported outcomes. Both arms of the study will include basic physician education (academic detailing) and electronic clinical decision support. In Arm 1, the investigators will implement an electronic referral system (electronic referral), in which specialists will electronically review referrals and make additional recommendations if appropriate primary UI care was not provided. In Arm 2, Advanced Practice Provider (APP) co-management will reduce the burden of care on the PCPs by providing UI care, patient education, and assisting with patient self-management through dedicated televisits (APP co-management).

NCT ID: NCT05948397 Not yet recruiting - Quality of Life Clinical Trials

To Use the Combined Version of ICIQ-SF and Quality of Life Scale in Mixed Urinary Incontinence

Start date: August 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is detecting the dominant component of mixed urinary incontinence via a combined version of ICIQ-SF and quality of life scale. The main question it aims to answer is: 1. Which component (urgency or stress) urinary incontinence bothers the patient more?

NCT ID: NCT05938855 Not yet recruiting - Clinical trials for Urinary Incontinence

Performance and Safety of the PHENIX LIBERTY, a Medical Device for Electrostimulation and Biofeedback, in the Treatment of Pelvic Static Disorders in Women With Urinary Incontinence.

IncontiLib
Start date: April 10, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the short-term improvement in urinary incontinence after perineo-sphincter rehabilitation using functional electrostimulation and biofeedback (PHENIX LIBERTY VIVALTIS device) in patients with pelvic statics disorders. • Does the use of the medical device in the treatment of pelvic static disorders lead to an improvement in urinary incontinence? Participants will use the medical device, which provides electrical stimulation, biofeedback and pressure biofeedback to re-educate the pelvic floor muscles and improve urinary incontinence.

NCT ID: NCT05773716 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Electroacupuncture and Pelvic Floor Muscle Training for Male Stress Urinary Incontinence

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical study is to compare the effects of combined electroacupuncture with pelvic floor muscle training (PFMT) versus PFMT alone in the treatment of involuntary urine leakage following prostate removal procedure due to prostate cancer. The main question it aims to answer is that whether adding electroacupuncture to PFMT provides extra benefits in relieve urinary leakage and improves patients' quality of life. All participants will be required to perform daily PFMT for 6 weeks using uniformed standards. During the meantime, those assigned to the experimental group will additionally receive electroacupuncture three times per week for 6 weeks, while those in control group will receive sham treatment with same duration. Researchers will compare the urine leakage severity between the two groups to see if adding electroacupuncture can facilitate the recovery of symptom.

NCT ID: NCT05719220 Not yet recruiting - Clinical trials for Urinary Incontinence

Effect of Group Preoperative Pelvic Floor Training for HoLEP

Start date: June 2023
Phase:
Study type: Observational

The main goal of this study is to see if group pelvic floor training before surgery can help prevent urinary incontinence after Holmium laser enucleation of the prostate (HoLEP) surgery. The study has the potential to inform preoperative intervention strategies for managing incontinence after HoLEP.

NCT ID: NCT05670392 Not yet recruiting - Clinical trials for Stress Urinary Incontinence

Laser and High Intensity Tesla Magnetic Stimulation (HITS) for Stress Urinary Incontinence (SUI)

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

To investigate the efficacy of combined laser and HITS treatment for female stress urinary incontinence (SUI)