Endotracheal Intubation Clinical Trial
Official title:
Screen and Intervene: A Diagnostic Accuracy Study and A Randomized, Open-label, Controlled Trial for Postextubation Dysphagia
Verified date | August 2020 |
Source | National Taiwan University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This clinical trial aims to test the validity of a two-item swallowing screen and to examine the effects of the Swallowing and Oral-Care (SOC) Program on resumption of oral intake, incidence of penetration and aspiration, and incidence of pneumonia in adult patients who successfully extubated after ≥ 48 hours of endotracheal intubation.
Status | Completed |
Enrollment | 145 |
Est. completion date | August 8, 2020 |
Est. primary completion date | August 8, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years and older |
Eligibility | Inclusion Criteria: - Patient who is over 20 years old. - Patient how has received over 48 hours endotracheal intubation and had been successfully extubated. Exclusion Criteria: - Patient who has a history of neuromuscular disease (e.g., parkinsonism or stroke) or head and neck deformities. - Patient who has preexisting difficulty swallowing. - Patient who has received a tracheostomy. - Patient who were unable to follow verbal instructions. - Patient who were on contact and droplet precautions (e.g., open tuberculosis) - Patient who were receiving continuous noninvasive ventilation after extubation that precluded the delivery of an SOC intervention |
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital | Ministry of Science and Technology, Taiwan |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Resumption of oral feeding | Measured by Functional Oral Intake Scale | Postextubation 7 days | |
Primary | Incidence of penetration and aspiration | Measured by the Fiberoptic endoscopic evaluation of swallowing (FEES) with optional and the study participants either opt-in or opt-out for this procedure, given that its invasive-nature procedure. | Time points of assessments: within 48 hrs postextubation and at the day 10 postextubation | |
Primary | Incidence of pneumonia | Abstracted from electronic medical records, based on the American Thoracic Society/Infectious Diseases Society of America criteria. | Postextubation 30 days | |
Secondary | Incidence of feeding tube dependency | Abstracted from electronic medical records | Postextubation 30 days | |
Secondary | Unstimulated salivary flow rate (centimeter/5 minutes) | Measured by the whatman 41 test strip | Time points of assessments: within 48 hours postextubation and at the day 10 postextubation | |
Secondary | Oral health status score | Measured by the oral Assessment Guide | Time points of assessments: within 48 hours postextubation and at the day 10 postextubation | |
Secondary | Lip closure and lingual diadochokinetic status | Measured by the Frenchay Dysarthria Assessment | Time points of assessments: within 48 hours postextubation and at the day 10 postextubation |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT06089187 -
Comparing Endotracheal Tube Cuff Pressure in Laparoscopic Abdominal Surgery: Saline vs. Air Inflation
|
N/A | |
Completed |
NCT02395445 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Routine Airway Management
|
N/A | |
Completed |
NCT02395432 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Difficult Airway
|
N/A | |
Unknown status |
NCT01041066 -
Nicardipine Versus Labetalol During Intubation
|
N/A | |
Recruiting |
NCT02395406 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Difficult Airway Management
|
N/A | |
Recruiting |
NCT02395419 -
A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Routine Airway Management
|
N/A | |
Enrolling by invitation |
NCT02277015 -
Intubation During Pediatric Resuscitation
|
N/A | |
Completed |
NCT01169467 -
Cerebral Perfusion Pressure Using Precedex and Other Sedatives
|
Phase 3 | |
Completed |
NCT00620386 -
Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade
|
Phase 2/Phase 3 | |
Completed |
NCT05069844 -
Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation
|
N/A | |
Enrolling by invitation |
NCT05620108 -
Intubating Conditions of Neuromuscular Blockade
|
N/A | |
Completed |
NCT02741921 -
Conventional Double-lumen Tube vs VivaSight DL
|
N/A | |
Recruiting |
NCT02295657 -
Double Lumen Tube Intubation
|
N/A | |
Completed |
NCT01488370 -
Comparison of 2 Laryngoscopes for Endotracheal Intubation in Children Younger Than 2 Years Old
|
N/A | |
Recruiting |
NCT01006668 -
Sevoflurane Versus Propofol for Intubation in Neonatal Intensive Care
|
Phase 3 | |
Recruiting |
NCT04483895 -
Comparison Between the Oro-Helical Length Technique and the 7-8-9 Rule in Determination of the Ideal Endotracheal Tube Insertion Depth in Neonates
|
N/A | |
Completed |
NCT04141267 -
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
|
||
Completed |
NCT01490580 -
Premedication Trial for Tracheal Intubation of the NEOnate
|
Phase 2/Phase 3 | |
Completed |
NCT03878797 -
The Depth of Endotracheal Tube Insertion
|
||
Not yet recruiting |
NCT05495880 -
Forearm-Supported Head Extension to Decrease Dental Contact
|
N/A |