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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06372262
Other study ID # Rowers2022
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 1, 2022
Est. completion date June 30, 2022

Study information

Verified date June 2022
Source Poznan University of Physical Education
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The study aimed to check the 2000m ergometer test on markers of gut permeability in the competitive phase of rowers. 18 members of the Polish rowing team took part in the study.


Description:

The phenomenon of epithelial wall leakage has been the subject of investigations within athletic domains such as running and cycling. Nevertheless, there exists an insufficiency of understanding regarding gut permeability in alternative disciplines, such as rowing, particularly following the completion of a standard competitive distance of 2000 meters. Hence, the principal objective of our study was to assess gut permeability after completing a 2000-meter rowing test. The study was performed at the beginning of a competitive training phase. Eighteen elite Polish Rowing Team rowers participated in the study after applying the inclusion/exclusion criteria. The participants performed a 2000-meter ergometer test. Blood samples were taken before the test, after exercise, and after 1-hour of restitution. Parameters, such as I-FABP, LPS, LBP, and zonulin, were determined using appropriate biochemical tests.


Recruitment information / eligibility

Status Completed
Enrollment 18
Est. completion date June 30, 2022
Est. primary completion date June 30, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 18 Years to 23 Years
Eligibility Inclusion Criteria: - minimum five years of training, - five training sessions per week minimum, - total training time minimum of 240 minutes, - membership in the Polish Rowing Team, - finishing the 2000-meter ergometer test. Exclusion Criteria: - antibiotic therapy within the last three months, - probiotics and prebiotics within the last three months, - dietary regime, - gastrointestinal diseases.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
ergometer test
2000meter rowing ergometer test

Locations

Country Name City State
Poland Poznan University of Physical Education Poznan

Sponsors (1)

Lead Sponsor Collaborator
Poznan University of Physical Education

Country where clinical trial is conducted

Poland, 

Outcome

Type Measure Description Time frame Safety issue
Primary I-FABP (intestinal fatty acid binding protein)to measure epithelial wall injury I-FABP concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period
Primary zonulin to measure tight junction leakage zonulin concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period
Primary LBP (lipopolysaccharide binding protein) to measure endotoxin LBP concentration measured in blood [ug/ml] using commercially available enzyme-linked immunosorbent assays Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period
Primary LPS (lipopolysaccharide) to measure endotoxin LPS concentration measured in blood [EU/Ll] using commercially available enzyme-linked immunosorbent assays Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting), one minute after the end of the test, and after a 1-hour recovery period
Primary Lactic acid to measure fatigue after the race Lactate concentration measured in capillary blood from earlobe [mmol/L] using a commercially available kit (Diaglobal, Berlin, Germany) Blood samples was taken from earlobe at two-time points: before each stress test (after overnight fasting), one minute after the end of the test.
Secondary energy energy [kcal ]of food intake measured by 24h dietary recall day before test
Secondary fiber intake fiber [g] intake day before the test measured by 24h dietary recall day before test
Secondary protein protein [g] intake day before the test measured by 24h dietary recall day before test
Secondary carbohydrate carbohydrate [g] intake day before the test measured by 24h dietary recall day before test
Secondary body mass Body mass [kg] measured by electronic scale to the nearest 0,05 kg (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan). in the morning before the test
Secondary Body composition - water % of body water measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan). in the morning before the test
Secondary Body composition - fat % of body fat measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan). in the morning before the test
Secondary Lean body mass Lean body mass [kg] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan). in the morning before the test
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