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Endophthalmitis Cultures — PROSPER  

Endophthalmitis Clinical Trial

Official title:
Prospective Surveillance of Patients With Endophthalmitis for Multi-antibiotic Resistance (PROSPER) Study

Clinical Trial Summary

The intent of this surveillance study will be to obtain written permission from patients with bacterial endophthalmitis in order to compare sterilization rates of their cultured bacterial isolates to standard therapy (vancomycin and ceftazidime) versus combination therapy with vancomycin, ceftazidime, and moxifloxacin.

Research hypothesis:

1. Cultured bacterial isolates will demonstrate faster in vitro sterilization rates with combination treatment (vancomycin, ceftazidime, and moxifloxacin) compared to "standard therapy" with vancomycin and ceftazidime.

2. Longitudinal analysis of resistance patterns of cultured isolates will show increasing rates of multi-antibiotic resistance.

Clinical Trial Description

Adult patients over 18 years of age presenting with endophthalmitis and able to sign consent. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01496794
Study type Observational
Source Vanderbilt University Medical Center
Contact
Status Terminated
Phase N/A
Start date October 2011
Completion date April 2016
View Details
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