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The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery

Endometriosis Clinical Trial

Official title:
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery: A Prospective, Randomized, Placebo-Controlled Trial

Clinical Trial Summary

The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.

Clinical Trial Description

The study is a prospective, randomized, placebo-controlled trial. Women scheduled for endometriosis surgery between 18-50 years of age will be invited to participate in the study. Participants with surgically staged endometriosis will be randomized to the metronidazole plus routine postoperative care arm or the placebo plus routine postoperative care arm. Participants will take study or placebo drug for a total of 14 days. Participants will complete surveys at baseline and postoperatively at 6 weeks, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years reporting intensity of endometriosis associated pain on a visual analog scale, pregnancy outcomes, quality of life, and sexual health. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04554693
Study type Interventional
Source University of Louisville
Contact Amira Quevedo, MD
Phone 5025884400
Email amira.quevedo@uoflhealth.org
Status Recruiting
Phase Phase 4
Start date October 19, 2020
Completion date September 2027
View Details
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