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Endometriosis clinical trials

View clinical trials related to Endometriosis.

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NCT ID: NCT00619866 Completed - Endometriosis, Pain Clinical Trials

An Efficacy and Safety Study of Elagolix (NBI-56418) in Women With Endometriosis

Start date: February 19, 2008
Phase: Phase 2
Study type: Interventional

This study is designed to see how elagolix works compared to placebo in women with endometriosis and to see the effect, if any, on bone mineral density.

NCT ID: NCT00604864 Completed - Endometriosis Clinical Trials

Effect of Anti TNFa Upon Deep Endometriosis Associated Pain

Infliximab
Start date: February 2004
Phase: Phase 2
Study type: Interventional

Deep endometriosis associated pain is believed to be caused by inflammation. Anti TNFa has been proved to be an effective treatment for other inflammation related conditions as Crohn's disease Endometriosis is associated with an inflammatory response in the pelvis, which is mediated by a number of cytokines including TNF-α. It has therefore been suggested that infliximab, an anti-TNF-α monoclonal antibody, might relieve pain in affected women.

NCT ID: NCT00556075 Terminated - Endometriosis Clinical Trials

Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis

Start date: November 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Proellex is safe and effective for the treatment of symptomatic endometriosis.

NCT ID: NCT00485355 Completed - Clinical trials for Uterine Fibroids, Menorrhagia, Endometriosis

Study Comparing Conventional vs. Robotic-assisted Laparoscopic Hysterectomy

Start date: June 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two ways of performing laparoscopic hysterectomy - robotic-assisted vs. conventional laparoscopy.

NCT ID: NCT00474851 Completed - Endometriosis Clinical Trials

The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial

Start date: August 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether a regimen of norethindrone acetate + placebo or norethindrone acetate + conjugated estrogens is superior in maintaining skeletal health and quality of life in adolescents treated with a GnRH agonist for endometriosis.

NCT ID: NCT00464139 Completed - Infertility Clinical Trials

Prevalence of Endometriosis in a Well Defined Group of Infertile Women

Start date: January 2007
Phase: N/A
Study type: Observational

At the Leuven University Fertility Centre (LUFC) of the Department of Obstetrics and Gynecology of the University Hospitals Leuven, Belgium, a retrospective epidemiological prevalence study based on an electronic search of patient files was performed to determine the prevalence of histologically proven endometriosis in a subset of infertile women with a regular cycle (variation 21 - 35 days), a partner with normal sperm and no previous surgical diagnosis of endometriosis.

NCT ID: NCT00463398 Recruiting - Endometriosis Clinical Trials

Fertility Surgery, Prospective Analysis

Start date: September 2006
Phase: N/A
Study type: Observational

From September 2006 a prospective cohort study is conducted among all patients operated at the Leuven University Fertility Centre to evaluate clinical and economical outcome after CO2 laser laparoscopic fertility surgery.

NCT ID: NCT00462176 Completed - Endometriosis Clinical Trials

Laparoscopic Segmental Bowel Resection for Deep Infiltrating Colorectal Endometriosis

Start date: September 2004
Phase: N/A
Study type: Observational

This study is executed to evaluate the outcome on quality of life, pain, sexuality, pregnancy rate and recurrence rate after a fertility sparing multidisciplinary CO2 laser laparoscopic radical excision of deep infiltrating colorectal endometriosis with a bowel resection.

NCT ID: NCT00461838 Completed - Endometriosis Clinical Trials

Outcome After Multidisciplinary CO2 Laser Laparoscopic Excision of Deep Infiltrating Colorectal Endometriosis

Start date: September 1996
Phase: N/A
Study type: Observational

Improved pain, sexuality and quality of life, high fertility and low complication and recurrence rates after multidisciplinary CO2 laser laparoscopic excision of deep infiltrating colorectal endometriosis.

NCT ID: NCT00458458 Active, not recruiting - Endometriosis Clinical Trials

Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg)

Start date: August 2004
Phase: Phase 3
Study type: Interventional

(A) Major 1) to compare the effectiveness of norethindrone acetate (NA) with GnRH agonist (Lupron-Depot-3) in relieving symptoms of endometriosis, 2) to compare bone density in the two treated groups in order to demonstrate that NA does not affect bone density; (B) Minor: 1) To compare the lipid profiles of patients in the two groups to confirm the hypothesis that the effects of NA and GnRH agonists on lipid profiles are similar, 2) To determine whether quality of life, assessed by questionnaire, is better in patients assigned to NA than in patients assigned to GnRH, 3) To determine whether NA has fewer adverse effects than GnRH agonist.