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Surgical Compared to Bronchoscopic Lung Volume Reduction in Patients With Severe Emphysema — SINCERE  

Emphysema Clinical Trial

Official title:
Surgical Compared to Bronchoscopic Lung Volume Reduction in Patients With Severe Emphysema: an International Multi-center Randomized Controlled Trial

Clinical Trial Summary

The investigators plan to perform a randomized controlled trial that compares bilateral lung volume reduction surgery (LVRS) with bronchoscopic lung volume reduction (BLVR) using endobronchial valves in terms of efficacy and patient safety.

Clinical Trial Description

Advanced lung emphysema has a considerable impact on quality of life in patients with chronic obstructive pulmonary disease. There are positive reports of surgical as well as bronchoscopic volume reduction in selected patients, but data comparing LVRS and BLVR is unfortunately lacking to date. The investigators therefore anticipate that their study will make an important contribution to the worldwide efforts in better understanding selection and management of surgical and bronchoscopic treatment of emphysema patients and that it will be of high public interest. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04537182
Study type Interventional
Source University of Zurich
Contact Isabelle Opitz, Prof. MD
Phone +41 44 255 11 11
Email isabelle.schmitt-opitz@usz.ch
Status Recruiting
Phase N/A
Start date September 1, 2020
Completion date March 2028
View Details
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